HsaEX6007442 @ hg19
Exon Skipping
Gene
ENSG00000136237 | RAPGEF5
Description
Rap guanine nucleotide exchange factor (GEF) 5 [Source:HGNC Symbol;Acc:16862]
Coordinates
chr7:22232985-22259610:-
Coord C1 exon
chr7:22259485-22259610
Coord A exon
chr7:22233533-22233651
Coord C2 exon
chr7:22232985-22233073
Length
119 bp
Sequences
Splice sites
3' ss Seq
ATCCCTGTCCACAATTAAAGCAA
3' ss Score
3.82
5' ss Seq
GAGGTGAGA
5' ss Score
7.66
Exon sequences
Seq C1 exon
GCAGGGGTGATGTGCAAGCTCCAGGAAAGAGATGAAATCGGACGAATTGAACTAGTCCAGAAGCTGGCAAAAGAAAACTATCAGTTTTTGCAGACGGACAAAAAAGAACAGGAGAAGTCTGAACAC
Seq A exon
CAAGATGATGAAGTGACGACTGTTCAGGTTAAAGAGCAAGACCAGAGCGTCCTGGTGCTGAAGAAAGTGCAGTGCTGTGGCCCAGCCCCCACAGCTGGGAGTGCGGAGAGCCATTGGAG
Seq C2 exon
ATATGTGGTGGTGTCCGGGACCCCGGAGAAGATTTTGGAGCACCTTTTGAATGACTTGCACCTGGAAGAAGTCCAGGACAAAGAAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136237-'13-20,'13-15,16-20=AN
Average complexity
A_S
Mappability confidence:
93%=100=88%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.317 A=0.242 C2=0.087
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0061815=RasGEF_N=PU(25.5=90.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGGGGTGATGTGCAAGCTC
R:
TTCTTTGTCCTGGACTTCTTCC
Band lengths:
210-329
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)