HsaEX6015727 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:141013556-141020102:-
Coord C1 exon
chr2:141019922-141020102
Coord A exon
chr2:141015696-141015915
Coord C2 exon
chr2:141013556-141013745
Length
220 bp
Sequences
Splice sites
3' ss Seq
TTGTTTTTTTAATGTCTTAGTTG
3' ss Score
6.84
5' ss Seq
AAGGTAAAA
5' ss Score
8.38
Exon sequences
Seq C1 exon
ATCTGGATAATGTAGAGGGCATTGCTGTGGACTGGATTGGAAATAATCTTTACTGGACCAATGATGGCCATAGGAAAACCATTAATGTGGCCAGGCTGGAAAAAGCTTCTCAGAGTCGGAAGACTCTTTTAGAGGGTGAAATGTCTCATCCCAGAGGAATTGTGGTGGATCCAGTTAATGG
Seq A exon
TTGGATGTATTGGACAGACTGGGAGGAAGATGAAATAGATGACAGCGTGGGAAGGATTGAGAAGGCCTGGATGGATGGATTCAATCGGCAGATTTTTGTGACTTCAAAGATGCTGTGGCCAAACGGTTTAACTCTGGACTTTCACACCAACACATTATACTGGTGTGATGCCTATTACGATCATATTGAAAAAGTATTTTTGAATGGGACTCACAGGAAG
Seq C2 exon
ATTGTTTACAGTGGGAGAGAGTTGAACCACCCTTTCGGACTGTCGCATCATGGAAATTATGTGTTCTGGACTGATTATATGAATGGTTCCATTTTTCAACTAGATTTGATAACAAGTGAGGTGACATTGCTGAGGCATGAAAGACCACCCCTATTTGGGCTTCAGATTTATGATCCACGAAAGCAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'26-50,'26-49,27-50=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(26.8=18.0),PF0005812=Ldl_recept_b=WD(100=72.1),PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
PF0005812=Ldl_recept_b=WD(100=64.9),PF0005812=Ldl_recept_b=PU(60.5=31.1)
C2:
PF0005812=Ldl_recept_b=PD(34.2=20.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTAGAGGGCATTGCTGTGGAC
R:
GCCTCAGCAATGTCACCTCAC
Band lengths:
306-526
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains