MmuEX6101021 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:41468822-41476815:-
Coord C1 exon
chr2:41476635-41476815
Coord A exon
chr2:41470942-41471161
Coord C2 exon
chr2:41468822-41469011
Length
220 bp
Sequences
Splice sites
3' ss Seq
TCTTGTTTCTCACTTCCTAGTTG
3' ss Score
8.14
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
Exon sequences
Seq C1 exon
ATCTGGATAATGTAGAAGGTATTGCAGTGGACTGGATTGGAAATAACCTTTATTGGACCAATGATGGTCACAGAAAAACCATCAATGTGGCCAGGCTGGAAAAGGCTTCTCAGAGCCGGAAAACTCTGCTGGAAGGAGGAATGTCTCATCCAAGAGCAATTGTGGTAGATCCAGTCAACGG
Seq A exon
TTGGATGTACTGGACAGACTGGAAGGAAGATAAAATAGATGACAGCGTGGGAAGGATTGAGAAAGCTTGGATGGATGGTGTCAATCGACAGGTTTTTGTGACTTCAAAGATGCTGTGGCCAAATGGCTTAACACTGGACTTTCACACCAGCACATTATATTGGTGTGATGCTTACTATGATCATATTGAGAAAGTATTTTTGAATGGAACCCACAGAAAG
Seq C2 exon
GTTGTATACAGTGGTAAAGAGCTGAACCATCCTTTTGGACTGTCACATCATGGGAATTATGTGTTCTGGACAGATTACATGAATGGTTCAATTTTTCAACTAGATTTGATGACCAATGAGGTGACGTTGCTGAGGCATGAAAGAGCACCCCTGTTTGGGCTTCAGATTTATGATCCACGAAAACAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'28-23,'28-22,29-23
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(26.8=18.0),PF0005812=Ldl_recept_b=WD(100=72.1),PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
PF0005812=Ldl_recept_b=WD(100=64.9),PF0005812=Ldl_recept_b=PU(60.5=31.1)
C2:
PF0005812=Ldl_recept_b=PD(34.2=20.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCAGTGGACTGGATTGGAAA
R:
TCAGCAACGTCACCTCATTGG
Band lengths:
292-512
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types