HsaEX6015731 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:140902920-140923147:-
Coord C1 exon
chr2:140922965-140923147
Coord A exon
chr2:140907877-140908077
Coord C2 exon
chr2:140902920-140903165
Length
201 bp
Sequences
Splice sites
3' ss Seq
ACTATTTCTGTTTTCTTAAGGGA
3' ss Score
8.11
5' ss Seq
GTGGTATTG
5' ss Score
1.72
Exon sequences
Seq C1 exon
AGATTCATTCTCCTGCTGGTTGTAACGGAAATGAATTTCAGTGCCACCCTGATGGTAATTGCGTTCCTGATTTGTGGCGCTGTGATGGAGAAAAAGACTGTGAAGATGGTAGTGATGAAAAAGGTTGCAATGGTACCATACGATTGTGTGACCACAAAACCAAGTTTTCCTGTTGGAGTACAG
Seq A exon
GGAGATGCATCAACAAAGCATGGGTGTGTGATGGAGATATTGATTGCGAAGATCAGTCAGATGAAGATGACTGTGACAGTTTCTTGTGTGGACCACCCAAGCATCCTTGTGCTAATGACACCTCAGTCTGCCTGCAGCCAGAGAAACTCTGCAATGGGAAAAAGGATTGTCCTGATGGCTCTGATGAAGGCTATCTCTGTG
Seq C2 exon
ATGAGTGTTCGCTGAACAATGGAGGCTGTAGCAACCACTGTTCTGTTGTTCCTGGAAGAGGAATTGTCTGTTCCTGCCCTGAAGGACTTCAACTCAACAAAGACAATAAAACATGTGAAATTGTGGATTATTGTAGCAATCATCTAAAGTGCAGCCAAGTATGTGAGCAGCACAAGCACACAGTCAAGTGCTCATGTTATGAAGGTTGGAAGCTGGATGTAGACGGTGAAAGTTGTACAAGTGTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'33-66,'33-61,37-66=AN
Average complexity
A_C2
Mappability confidence:
87%=86=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=WD(100=61.3),PF0005713=Ldl_recept_a=PU(35.9=22.6)
A:
PF0005713=Ldl_recept_a=PD(61.5=35.3),PF0005713=Ldl_recept_a=PU(92.9=57.4)
C2:
PF0005713=Ldl_recept_a=PD(4.8=2.4),PF146701=FXa_inhibition=WD(100=44.6),PF146701=FXa_inhibition=WD(100=42.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCCAGGAGTGTTCCATTACAC
R:
GTCCCACCGTCAAGCCATC
Band lengths:
198-399
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains