HsaEX6015732 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:140886138-140908077:-
Coord C1 exon
chr2:140907877-140908077
Coord A exon
chr2:140902920-140903165
Coord C2 exon
chr2:140886138-140886335
Length
246 bp
Sequences
Splice sites
3' ss Seq
CTGTTCCCCCCTTTTTATAGATG
3' ss Score
10.39
5' ss Seq
TTGGTAAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
GGAGATGCATCAACAAAGCATGGGTGTGTGATGGAGATATTGATTGCGAAGATCAGTCAGATGAAGATGACTGTGACAGTTTCTTGTGTGGACCACCCAAGCATCCTTGTGCTAATGACACCTCAGTCTGCCTGCAGCCAGAGAAACTCTGCAATGGGAAAAAGGATTGTCCTGATGGCTCTGATGAAGGCTATCTCTGTG
Seq A exon
ATGAGTGTTCGCTGAACAATGGAGGCTGTAGCAACCACTGTTCTGTTGTTCCTGGAAGAGGAATTGTCTGTTCCTGCCCTGAAGGACTTCAACTCAACAAAGACAATAAAACATGTGAAATTGTGGATTATTGTAGCAATCATCTAAAGTGCAGCCAAGTATGTGAGCAGCACAAGCACACAGTCAAGTGCTCATGTTATGAAGGTTGGAAGCTGGATGTAGACGGTGAAAGTTGTACAAGTGTTG
Seq C2 exon
ATCCTTTTGAAGCATTCATCATCTTTTCTATTCGTCATGAGATCAGAAGGATTGATCTTCACAAAAGAGACTATAGTCTACTTGTTCCTGGATTGAGAAACACAATAGCACTTGATTTTCACTTCAATCAAAGTTTACTTTATTGGACAGATGTTGTAGAAGACAGAATATACCGGGGAAAGCTTTCTGAAAGTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'33-68,'33-63,39-68=AN
Average complexity
A_C3
Mappability confidence:
76%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=PD(61.5=35.3),PF0005713=Ldl_recept_a=PU(92.9=57.4)
A:
PF0005713=Ldl_recept_a=PD(4.8=2.4),PF146701=FXa_inhibition=WD(100=44.6),PF146701=FXa_inhibition=WD(100=42.2)
C2:
PF0005812=Ldl_recept_b=PU(48.9=32.8)
Main Skipping Isoform:
ENST00000389484fB19031
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCCAGGAGTGTTCCATTACAC
R:
TTTCAGAAAGCTTTCCCCGGT
Band lengths:
292-538
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains