MmuEX6101030 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:41312476-41344618:-
Coord C1 exon
chr2:41344418-41344618
Coord A exon
chr2:41341691-41341936
Coord C2 exon
chr2:41312476-41312673
Length
246 bp
Sequences
Splice sites
3' ss Seq
AAGTATCTGTCCCTTTACAGATG
3' ss Score
10.34
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
Exon sequences
Seq C1 exon
GGAGATGCATCAACAATGCCTGGGTATGTGATGGAGATGTTGACTGTGAAGATCAGTCTGATGAAGAAGACTGTGACAGTTTCTTGTGTGGACCACCCAAGTACCCTTGTGCTAATGACACCTCTGTGTGCCTGCAGCCAGAGAAACTCTGCAATGGGAGGAAGGACTGTCCAGATGGGTCAGATGAAGGCGACCTTTGTG
Seq A exon
ATGAGTGTTCTCTGAACAATGGAGGGTGTAGCAACCACTGTTCTGTTGTTCCTGGAAGAGGAATTGTCTGTTCCTGCCCAGAAGGACATCAGCTCAAGAAAGACAATAGAACATGTGAAATCGTGGACTACTGTGCCTCCCACCTGAGGTGCAGCCAAGTGTGTGAGCAGCAAAAACATATGGTCAAGTGCTCCTGCTATGAAGGCTGGGCGTTGGGGACTGATGGGGAAAGCTGCACCAGTGTGG
Seq C2 exon
ATTCTTTTGAGGCATTCATCATCTTTTCTATACGCCATGAAATTCGAAGGATTGATCTGCATAAAGGAGACTACAGCCTACTTGTTCCTGGACTGAGAAATACCATAGCACTTGATTTTCACTTCAATCAAAGTTTACTTTACTGGACAGATGTTGTGGAAGACAGAATATACAGGGGCAAGCTGTCAGAGAGTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'42-38,'42-37,43-38=AN
Average complexity
A_C3
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=PD(61.5=35.3),PF0005713=Ldl_recept_a=PU(92.9=57.4)
A:
PF0005713=Ldl_recept_a=PD(4.8=2.4),PF146701=FXa_inhibition=WD(100=44.6),PF146701=FXa_inhibition=WD(100=41.0)
C2:
PF0005812=Ldl_recept_b=PU(48.9=32.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCTTTCCTTCTTTCTTCCTTCCT
R:
AACTGTCTCTAGTCCCGTCCC
Band lengths:
292-538
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types