HsaEX6015747 @ hg19
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
low density lipoprotein receptor-related protein 1B [Source:HGNC Symbol;Acc:6693]
Coordinates
chr2:141459290-141460122:-
Coord C1 exon
chr2:141459996-141460122
Coord A exon
chr2:141459710-141459861
Coord C2 exon
chr2:141459290-141459414
Length
152 bp
Sequences
Splice sites
3' ss Seq
ACTTCTTAATCGATATTTAGGAA
3' ss Score
6.27
5' ss Seq
CAGGTAATT
5' ss Score
8.55
Exon sequences
Seq C1 exon
CCTCTTGTTCTGGACTGAATGGGGACAAATGCCCTGTATTGGAAAGGCTCGCTTGGATGGCTCAGAGAAGGTTGTCCTTGTAAGCATGGGAATAGCATGGCCGAATGGCATCTCCATCGACTATGAG
Seq A exon
GAAAATAAATTGTACTGGTGTGATGCTCGCACAGACAAGATAGAGAGAATCGACCTTGAGACTGGAGGGAATCGCGAGATGGTGCTGTCAGGAAGCAATGTGGATATGTTTTCAGTTGCAGTCTTTGGGGCTTACATCTACTGGTCTGACAG
Seq C2 exon
AGCACATGCAAACGGGTCTGTCAGAAGGGGCCACAAGAATGATGCCACAGAAACGATAACCATGAGAACCGGCCTTGGAGTCAACCTGAAGGAGGTTAAAATATTTAACCGAGTAAGAGAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'39-39,'39-38,40-39=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.163
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=97.7)
A:
PF0005812=Ldl_recept_b=WD(100=78.4)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCTTGTTCTGGACTGAATGGGG
R:
CCTTCAGGTTGACTCCAAGGC
Band lengths:
218-370
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)