MmuEX6101046 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:41112259-41113094:-
Coord C1 exon
chr2:41112968-41113094
Coord A exon
chr2:41112684-41112835
Coord C2 exon
chr2:41112259-41112383
Length
152 bp
Sequences
Splice sites
3' ss Seq
GCTTTCCAATCACCTTTTAGGAA
3' ss Score
9.76
5' ss Seq
CAGGTAATT
5' ss Score
8.55
Exon sequences
Seq C1 exon
CTTCTTGTTCTGGACTGAATGGGGACAAGTGCCTTGTATTGGGAAAGCTCGCTTAGATGGTTCTGAGAAGGTCATGATTGTAAGCGTGGGAATAACATGGCCCAATGGCATCTCCATTGACTATGAG
Seq A exon
GAAAATAAATTATACTGGTGTGATGCTCGCTCAGACAAGATAGAGAGAATTGACCTTGACACTGGTGCGAATCGTGAAGTGTTGCTGTCTGGGAGCAACGTGGATCTGTTTTCAGTTGCAGTCTTTGGGGCTTACATCTACTGGTCTGACAG
Seq C2 exon
AGCACACGCCAATGGATCAGTCAGAAGAGGCCACAAGAATGATGCCACAGAGACAGTAACCATGAGAACAGGACTTGGAGTTAACCTAAAGGAGATCAAAATTTTTAACCGAGTAAGAGAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'63-60,'63-59,64-60=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.209
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=97.7)
A:
PF0005812=Ldl_recept_b=WD(100=80.4)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCTTGTTCTGGACTGAATGGGG
R:
TACTCGGTTAAAAATTTTGATCTCCT
Band lengths:
242-394
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types