HsaEX6015764 @ hg19
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
low density lipoprotein receptor-related protein 1B [Source:HGNC Symbol;Acc:6693]
Coordinates
chr2:141232707-141245308:-
Coord C1 exon
chr2:141245186-141245308
Coord A exon
chr2:141242912-141243093
Coord C2 exon
chr2:141232707-141232906
Length
182 bp
Sequences
Splice sites
3' ss Seq
TTTAAATTCTTGTTTTGTAGGTA
3' ss Score
9.21
5' ss Seq
TGGGTTTGT
5' ss Score
0.77
Exon sequences
Seq C1 exon
GGATTAAACAATGTTATTGCTATAGACTTTGATTACAGAGAAGAATTCATCTATTGGATCGATTCTAGCCGACCCAATGGCAGTCGCATAAATAGAATGTGTTTAAATGGAAGTGACATTAAG
Seq A exon
GTAGTTCATAACACAGCGGTCCCCAATGCACTTGCTGTCGATTGGATTGGAAAAAACCTCTATTGGTCTGACACAGAAAAAAGAATCATTGAAGTATCCAAACTCAATGGCTTGTACCCTACTATACTCGTTAGCAAAAGGCTGAAGTTTCCCAGAGACTTGTCTTTAGATCCTCAAGCTGG
Seq C2 exon
ATATTTGTATTGGATTGACTGCTGCGAGTATCCTCATATTGGCCGTGTTGGAATGGATGGAACCAATCAGAGTGTTGTCATAGAAACCAAGATTTCTAGACCTATGGCACTAACAATAGATTATGTTAATCGTAGACTCTACTGGGCCGATGAAAATCACATTGAATTTAGCAACATGGATGGATCTCATAGACACAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'59-59,'59-58,60-59=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.029
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PU(61.9=63.4)
A:
PF0005812=Ldl_recept_b=PD(33.3=23.0),PF0005812=Ldl_recept_b=WD(100=67.2),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=61.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACCCAATGGCAGTCGCATAA
R:
ATGAGATCCATCCATGTTGCT
Band lengths:
243-425
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)