HsaEX6016173 @ hg19
Exon Skipping
Gene
ENSG00000136536 | MARCH7
Description
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:17393]
Coordinates
chr2:160602281-160609082:+
Coord C1 exon
chr2:160602281-160602448
Coord A exon
chr2:160604316-160605414
Coord C2 exon
chr2:160608913-160609082
Length
1099 bp
Sequences
Splice sites
3' ss Seq
TATCTTCCTTTCAAAAATAGATG
3' ss Score
7.21
5' ss Seq
GAGGTAAAT
5' ss Score
8.39
Exon sequences
Seq C1 exon
ATTCATCTTGGAGGCATAGTCAAGTTCCTAGATCTTCATCAATGGTACTTGGATCATTTGGAACAGACTTAATGAGAGAGAGGAGAGATTTGGAGAGAAGAACAGATTCCTCTATTAGTAATCTTATGGATTATAGTCACCGAAGTGGTGATTTCACAACTTCATCAT
Seq A exon
ATGTTCAAGACAGAGTTCCTTCATATTCACAAGGAGCAAGACCAAAAGAAAACTCAATGAGCACTTTACAGTTGAATACATCATCCACAAACCACCAATTGCCTTCTGAACATCAGACCATACTAAGTTCTAGGGACTCCAGAAATTCTTTAAGATCAAATTTTTCTTCAAGAGAATCAGAATCTTCCCGAAGCAATACGCAGCCTGGATTTTCTTACAGTTCAAGTAGAGATGAAGCCCCAATCATAAGCAATTCAGAAAGGGTTGTTTCATCTCAAAGACCATTTCAAGAATCTTCTGACAATGAAGGTAGGCGGACAACGAGGAGATTGCTGTCACGCATAGCTTCTAGCATGTCATCTACTTTTTTTTCACGAAGATCTAGTCAGGATTCCTTGAATACAAGATCATTGAATTCTGAAAATTCTTACGTTTCTCCAAGAATCTTGACAGCTTCACAGTCCCGTAGTAATGTACCATCAGCTTCTGAAGTTCCCGATAATAGGGCATCTGAAGCTTCTCAGGGATTTCGATTTCTTAGGCGAAGATGGGGTTTGTCATCTCTTAGCCACAATCATAGCTCTGAGTCAGATTCAGAAAATTTTAACCAAGAATCTGAAGGTAGAAATACAGGACCATGGTTATCTTCCTCACTTAGAAATAGATGCACACCTTTGTTCTCTAGAAGGAGGCGAGAGGGAAGAGATGAATCTTCAAGGATACCTACCTCTGATACATCATCTAGATCTCATATTTTTAGAAGAGAATCAAATGAAGTGGTTCACCTTGAAGCACAGAATGATCCTCTTGGAGCTGCTGCCAACAGACCACAAGCATCTGCAGCATCAAGCAGTGCCACAACAGGTGGCTCTACATCAGATTCGGCTCAAGGTGGAAGAAATACAGGAATATCAGGGATTCTTCCTGGTTCCTTATTCCGGTTTGCAGTCCCTCCAGCACTTGGGAGTAATTTGACCGACAATGTCATGATCACAGTAGATATTATTCCTTCAGGTTGGAATTCAGCTGATGGTAAAAGTGATAAAACTAAAAGTGCGCCTTCAAGAGATCCAGAAAGATTGCAGAAAATAAAAGAGAG
Seq C2 exon
CCTCCTTTTAGAGGACTCAGAAGAAGAAGAAGGTGACTTATGTAGAATTTGTCAAATGGCAGCTGCATCATCATCTAATTTGCTGATAGAGCCATGCAAGTGCACAGGAAGTTTGCAGTATGTCCACCAAGACTGTATGAAAAAGTGGTTACAGGCCAAAATTAACTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136536-'10-9,'10-8,12-9=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.965 A=0.807 C2=0.049
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF129062=RINGv=PU(76.8=74.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCTTGGAGGCATAGTCAAGTTCC
R:
CAGAGTTAATTTTGGCCTGTAACCAC
Band lengths:
334-1433
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)