HsaEX6016817 @ hg38
Exon Skipping
Gene
ENSG00000115966 | ATF2
Description
activating transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:784]
Coordinates
chr2:175113994-175118118:-
Coord C1 exon
chr2:175117990-175118118
Coord A exon
chr2:175114690-175114868
Coord C2 exon
chr2:175113994-175114108
Length
179 bp
Sequences
Splice sites
3' ss Seq
TTTATCTCATTGTTAAATAGGAA
3' ss Score
8.45
5' ss Seq
TGTGTAAGT
5' ss Score
7.65
Exon sequences
Seq C1 exon
ATGCCTCTAGATTTATCCCCTCTTGCAACACCTATCATAAGAAGCAAAATTGAGGAGCCTTCTGTTGTAGAAACAACTCACCAGGATAGTCCTTTACCTCACCCAGAGTCTACTACCAGTGATGAGAAG
Seq A exon
GAAGTACCATTGGCACAAACTGCACAGCCCACATCAGCTATTGTTCGTCCAGCATCATTACAGGTTCCCAATGTGCTGCTTACAAGTTCTGACTCAAGTGTAATTATTCAGCAGGCAGTACCTTCACCAACCTCAAGTACTGTAATCACCCAGGCACCATCCTCTAACAGGCCAATTGT
Seq C2 exon
CCCTGTACCAGGCCCATTTCCTCTTCTGTTACATCTTCCTAATGGACAAACCATGCCTGTTGCTATTCCTGCATCAATTACAAGTTCTAATGTGCATGTTCCAGCTGCAGTCCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115966-'39-35,'39-30,44-35
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.761 A=0.639 C2=0.785
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCTCTAGATTTATCCCCTCTTGC
R:
TGGGACTGCAGCTGGAACAT
Band lengths:
242-421
Functional annotations
There are 1 annotated functions for this event
PMID: 26538579
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: protein array. ELM ID: ELMI003089; ELM sequence: RPASLQV; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains