HsaEX6025977 @ hg19
Exon Skipping
Gene
ENSG00000186716 | BCR
Description
breakpoint cluster region [Source:HGNC Symbol;Acc:1014]
Coordinates
chr22:23653884-23656260:+
Coord C1 exon
chr22:23653884-23654023
Coord A exon
chr22:23655074-23655208
Coord C2 exon
chr22:23656155-23656260
Length
135 bp
Sequences
Splice sites
3' ss Seq
CATTTCCGTGCTCTTTCCAGATA
3' ss Score
10.19
5' ss Seq
TCGGTGAGC
5' ss Score
9.1
Exon sequences
Seq C1 exon
GAGAGAGAGGTCCAAGGTGCCCTACATCGTGCGCCAGTGCGTGGAGGAGATCGAGCGCCGAGGCATGGAGGAGGTGGGCATCTACCGCGTGTCCGGTGTGGCCACGGACATCCAGGCACTGAAGGCAGCCTTCGACGTCA
Seq A exon
ATAACAAGGACGTGTCGGTGATGATGAGCGAGATGGACGTGAACGCCATCGCAGGCACGCTGAAGCTGTACTTCCGTGAGCTGCCCGAGCCCCTCTTCACTGACGAGTTCTACCCCAACTTCGCAGAGGGCATCG
Seq C2 exon
CTCTTTCAGACCCGGTTGCAAAGGAGAGCTGCATGCTCAACCTGCTGCTGTCCCTGCCGGAGGCCAACCTGCTCACCTTCCTTTTCCTTCTGGACCACCTGAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186716-'42-51,'42-50,44-51=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0062022=RhoGAP=PU(26.1=83.3)
A:
PF0062022=RhoGAP=FE(29.4=100)
C2:
PF0062022=RhoGAP=FE(22.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGAGAGAGGTCCAAGGTGCC
R:
CTTTTCAGGTGGTCCAGAAGGA
Band lengths:
246-381
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)