HsaEX6032479 @ hg19
Exon Skipping
Gene
ENSG00000134215 | VAV3
Description
vav 3 guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:12659]
Coordinates
chr1:108299883-108307797:-
Coord C1 exon
chr1:108307698-108307797
Coord A exon
chr1:108303406-108303501
Coord C2 exon
chr1:108299883-108299951
Length
96 bp
Sequences
Splice sites
3' ss Seq
TTTTTAAAACATTTCATTAGGAA
3' ss Score
5.82
5' ss Seq
CAGGTATGT
5' ss Score
9.8
Exon sequences
Seq C1 exon
ATTGGTTATTTACGGGCAGTACTGCAGTGGAGTGGAGTCAGCCATCTCTAGTTTAGACTACATTTCTAAGACAAAAGAAGATGTCAAACTGAAATTAGAG
Seq A exon
GAATGTTCCAAAAGAGCAAATAATGGGAAATTTACTCTTCGAGACTTGCTTGTGGTTCCTATGCAACGTGTTTTAAAGTACCACCTTCTCCTCCAG
Seq C2 exon
GAACTGGTCAAACATACCACTGATCCGACTGAGAAGGCAAATCTGAAACTGGCTCTTGATGCCATGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134215-'11-12,'11-11,12-12=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0062115=RhoGEF=FE(18.9=100)
A:
PF0062115=RhoGEF=FE(17.7=100)
C2:
PF0062115=RhoGEF=FE(12.6=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGTTATTTACGGGCAGTACTG
R:
CTTCATGGCATCAAGAGCCAGT
Band lengths:
167-263
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)