HsaEX6035782 @ hg38
Exon Skipping
Gene
ENSG00000134376 | CRB1
Description
crumbs 1, cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:2343]
Coordinates
chr1:197421000-197438675:+
Coord C1 exon
chr1:197421000-197421956
Coord A exon
chr1:197435600-197435612
Coord C2 exon
chr1:197438547-197438675
Length
13 bp
Sequences
Splice sites
3' ss Seq
CTGTTTTGGAAATTTTACAGGAA
3' ss Score
7.22
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
CTTATCAATTCAGGTCAATAATCAGTCAAAGGTGCTTCTGTTCATTTCCCACAACACCAGCGATGGAGAGTGGCATTTCGTGGAGGTAATATTTGCAGAGGCTGTGACCCTTACCTTAATCGACGACTCCTGTAAGGAGAAATGCATCGCGAAAGCTCCTACTCCACTTGAAAGTGATCAATCAATATGTGCTTTTCAGAACTCCTTTTTGGGTGGTTTACCAGTGGGAATGACCAGCAATGGTGTTGCTCTGCTTAACTTCTATAATATGCCATCCACACCTTCGTTTGTAGGCTGTCTCCAAGACATTAAAATTGATTGGAATCACATTACCCTGGAGAACATCTCGTCTGGCTCATCATTAAATGTCAAGGCAGGCTGTGTGAGAAAGGATTGGTGTGAAAGCCAACCTTGTCAAAGCAGAGGACGCTGCATCAACTTGTGGCTGAGTTACCAGTGTGACTGCCACAGGCCCTATGAAGGCCCCAACTGTCTGAGAG
Seq A exon
GAAAATTTTGCAG
Seq C2 exon
ACAGAGCAGATTACCCTCAACAGTCTGTGGGAATGAGAAGACAAATCTCACTTGCTACAATGGAGGCAACTGCACAGAGTTCCAGACTGAATTAAAATGTATGTGCCGGCCAGGTTTTACTGGAGAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134376_MULTIEX1-13/13=9-C2
Average complexity
S
Mappability confidence:
100%=93=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.003 C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=PD(3.9=0.6),PF0000822=EGF=WD(100=7.5),PF0000822=EGF=WD(100=10.9),PF0221019=Laminin_G_2=WD(100=43.1),PF0000822=EGF=WD(100=9.7)
A:
NO
C2:
PF0000822=EGF=WD(100=68.9)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGAAGGCCCCAACTGTCTGA
R:
CTCTGTGCAGTTGCCTCCATT
Band lengths:
103-116
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains