HsaEX6035782 @ hg19
Exon Skipping
Gene
ENSG00000134376 | CRB1
Description
crumbs homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:2343]
Coordinates
chr1:197398579-197407805:+
Coord C1 exon
chr1:197398579-197398744
Coord A exon
chr1:197403836-197404742
Coord C2 exon
chr1:197407677-197407805
Length
907 bp
Sequences
Splice sites
3' ss Seq
TTATCACCTTCTCTCATTAGGTA
3' ss Score
10.21
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
TCCAACCCCTGTCACAATGGAGGTGTTTGCCATTCCCGGTGGGATGACTTCTCCTGTTCCTGTCCTGCCCTCACAAGTGGGAAAGCCTGTGAGGAGGTTCAGTGGTGTGGATTCAGCCCGTGTCCTCACGGAGCCCAGTGCCAGCCGGTGCTTCAAGGATTTGAAT
Seq A exon
GTATTGCAAATGCTGTTTTTAATGGACAAAGCGGTCAAATATTATTCAGAAGCAATGGGAATATTACCAGAGAACTCACCAATATCACATTTGGTTTCAGAACAAGGGATGCAAATGTAATAATATTGCATGCAGAAAAAGAGCCTGAATTTCTTAATATTAGCATTCAAGATTCCAGATTATTCTTTCAATTGCAAAGTGGCAACAGCTTTTATATGCTAAGTCTGACAAGTTTGCAGTCAGTGAATGATGGCACATGGCACGAAGTGACCCTTTCCATGACAGACCCACTGTCCCAGACCTCCAGGTGGCAAATGGAAGTGGACAACGAAACACCTTTTGTGACCAGCACAATTGCTACTGGAAGCCTCAACTTTTTGAAGGATAATACAGATATTTATGTGGGAGACAGAGCTATTGACAATATAAAGGGCCTGCAAGGGTGTCTAAGTACAATAGAAATCGGAGGCATTTATCTCTCTTACTTTGAAAATGTTCATGGTTTCATTAATAAACCTCAGGAAGAGCAATTTCTCAAAATCTCTACCAATTCAGTGGTCACTGGCTGTTTGCAGTTAAATGTCTGCAACTCCAACCCCTGTTTGCATGGAGGAAACTGTGAAGACATCTATAGCTCTTATCATTGCTCCTGTCCCTTGGGATGGTCAGGGAAACACTGTGAACTCAACATCGATGAATGCTTTTCAAACCCCTGTATCCATGGCAACTGCTCTGACAGAGTTGCAGCCTACCACTGCACATGTGAGCCTGGATACACTGGTGTGAACTGTGAAGTGGATATAGACAACTGCCAGAGTCACCAGTGTGCAAATGGAGCCACCTGCATTAGTCATACTAATGGCTATTCTTGCCTCTGTTTTGGAAATTTTACAGGAAAATTTTGCAG
Seq C2 exon
ACAGAGCAGATTACCCTCAACAGTCTGTGGGAATGAGAAGACAAATCTCACTTGCTACAATGGAGGCAACTGCACAGAGTTCCAGACTGAATTAAAATGTATGTGCCGGCCAGGTTTTACTGGAGAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134376-'13-12,'13-11,14-12=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.003 C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=PD(90.0=48.2)
A:
PF0221019=Laminin_G_2=WD(100=41.6),PF0000822=EGF=WD(100=10.2),PF0000822=EGF=WD(100=9.9),PF0000822=EGF=WD(100=10.2)
C2:
PF0000822=EGF=WD(100=68.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCAACCCCTGTCACAATGGA
R:
GTAAAACCTGGCCGGCACATA
Band lengths:
286-1193
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)