HsaEX6036224 @ hg19
Exon Skipping
Gene
ENSG00000133056 | PIK3C2B
Description
phosphoinositide-3-kinase, class 2, beta polypeptide [Source:HGNC Symbol;Acc:8972]
Coordinates
chr1:204413459-204416706:-
Coord C1 exon
chr1:204416564-204416706
Coord A exon
chr1:204415084-204415272
Coord C2 exon
chr1:204413459-204413552
Length
189 bp
Sequences
Splice sites
3' ss Seq
CCTTTCCGTGTGCCCACCAGGCT
3' ss Score
8.03
5' ss Seq
CACGTGAGT
5' ss Score
9.3
Exon sequences
Seq C1 exon
ATTGACTTCCCCACCTCGGCCTTTGACATCAAGTTCACCAGCCCCCCTGGAGACAAGTTCAGCCCCCGCTATGAGTTTGGCAGCCTCCGGGAAGAAGACCAGCGCAAGCTTAAAGACATCATGCAGAAAGAGTCCTTGTACTG
Seq A exon
GCTCACTGATGCTGACAAGAAGCGCCTGTGGGAGAAGCGATATTACTGCCACTCGGAGGTGAGCTCGCTCCCCCTGGTGCTCGCCAGCGCCCCCAGCTGGGAGTGGGCTTGCCTGCCTGACATCTATGTTCTCCTGAAGCAGTGGACCCACATGAACCACCAGGATGCCCTGGGGCTCCTGCATGCCAC
Seq C2 exon
CTTCCCGGACCAGGAGGTGCGTCGTATGGCTGTGCAGTGGATTGGCTCACTCTCAGATGCTGAGCTGCTAGACTACCTGCCCCAGCTGGTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133056-'27-27,'27-26,29-27=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0079219=PI3K_C2=PD(3.5=10.4),PF0061315=PI3Ka=PU(11.5=43.8)
A:
PF0061315=PI3Ka=FE(34.4=100)
C2:
PF0061315=PI3Ka=FE(16.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATTGACTTCCCCACCTCGGC
R:
CTGTACCAGCTGGGGCAG
Band lengths:
237-426
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)