HsaEX6036487 @ hg19
Exon Skipping
Gene
ENSG00000117335 | CD46
Description
CD46 molecule, complement regulatory protein [Source:HGNC Symbol;Acc:6953]
Coordinates
chr1:207930359-207933069:+
Coord C1 exon
chr1:207930359-207930547
Coord A exon
chr1:207930885-207930987
Coord C2 exon
chr1:207932984-207933069
Length
103 bp
Sequences
Splice sites
3' ss Seq
TCAAAATTATTTTCTTTCAGGAG
3' ss Score
8.5
5' ss Seq
GGGGTAAGT
5' ss Score
9.65
Exon sequences
Seq C1 exon
ATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATA
Seq A exon
GAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGG
Seq C2 exon
TTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000117335-'2-4,'2-3,3-4=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0008415=Sushi=WD(100=93.8),PF060117=TRP=FE(19.0=100)
A:
PF0008415=Sushi=PU(52.5=88.6),PF060117=TRP=FE(10.3=100)
C2:
PF0008415=Sushi=PD(45.8=90.0),PF060117=TRP=FE(8.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGTGAGGAGCCACCAACATT
R:
GGCTTACCGCTCCAAATTGCT
Band lengths:
257-360
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)