HsaEX6055550 @ hg19
Exon Skipping
Gene
ENSG00000188086 | PRSS45
Description
protease, serine, 45 [Source:HGNC Symbol;Acc:30717]
Coordinates
chr3:46783582-46786280:-
Coord C1 exon
chr3:46786133-46786280
Coord A exon
chr3:46784403-46784572
Coord C2 exon
chr3:46783582-46784073
Length
170 bp
Sequences
Splice sites
3' ss Seq
GTCACTGCTCACCCTGCTAGGCT
3' ss Score
6.36
5' ss Seq
TATGTGAGT
5' ss Score
5.56
Exon sequences
Seq C1 exon
TTTGTGGTGAGCCCTGGTGGTCGGAGGATTTGGAAATGACCCGCCATTGGCCCTGGGAGGTGAGCCTCCGGATGGAAAATGAGCACGTGTGTGGAGGGGCCCTCATTGACCCCAGCTGGGTGGTGACTGCGGCCCACTGCATCCAAGG
Seq A exon
GCTCCACAGCCAACTCCATGCTGACCCCAGAGCTGCAGGAGGCTGAGGTGTTTATCATGGACAACAAGAGGTGTGACCGGCATTACAAGAAGTCCTTCTTCCCCCCAGTTGTCCCCCTTGTCCTGGGGGACATGATCTGTGCCACCAATTATGGGGAAAACTTGTGCTAT
Seq C2 exon
GGGGATTCTGGAGGGCCATTGGCTTGTGAAGTTGAGGGCAGATGGATTCTGGCTGGGGTGTTGTCCTGGGAAAAGGCCTGCGTGAAGGCACAGAATCCAGGTGTGTACACCCGCATCACCAAATACACCAAATGGATCAAGAAGCAAATGAGCAATGGAGCCTTCTCAGGTCCCTGTGCCTCTGCCTGCCTCCTGTTCCTGTGCTGGCTGCTGCAGCCCCAGATGGGCTCCTGACCTCCCTACCTTTTCCTCCTCCTGCCTTGCCTCTGCTGAATGGGGCCAGATGGTTTGACCAAGGTCATGTGTCCATCTTCAAAAAGAGTCAGGGTGGGGAAGAGTAACCCCTGGGAGAATGGGTCTGGCTTTGGCATCCCGGTGAGGAGAAGTGTGGTGGATGACTAGGCCTTGGGTGAGCAGGAGAAGGGAAGTGTGGCCTAGAAGGATTCTGGAATCTGGGACCAGGAGAGCAGGGATTAAACATGTGCAAACTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188086-'6-10,'6-8,10-10=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.033 C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(34.9=97.4)
A:
PF0008921=Trypsin=PD(9.5=17.5),PF0008921=Trypsin=PU(53.5=94.7)
C2:
PF0008921=Trypsin=PD(44.6=57.7)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCGGATGGAAAATGAGCACG
R:
GACCTGAGAAGGCTCCATTGC
Band lengths:
254-424
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)