HsaEX6064271 @ hg19
Exon Skipping
Gene
ENSG00000188986 | COBRA1
Description
cofactor of BRCA1 [Source:HGNC Symbol;Acc:24324]
Coordinates
chr9:140161692-140167067:+
Coord C1 exon
chr9:140161692-140161798
Coord A exon
chr9:140166533-140166674
Coord C2 exon
chr9:140166959-140167067
Length
142 bp
Sequences
Splice sites
3' ss Seq
GATGCCTGCTGTGTCTGCAGTGG
3' ss Score
6.65
5' ss Seq
AAGGTAGGC
5' ss Score
10.08
Exon sequences
Seq C1 exon
GTTTCTGCAGGAGCAGCGCATGGCCTGCGAGGTGGGGCTGTACTACGTCCTGCACATCACCAAGCAGAGGAACAAGAACGCGCTCCTCCGCCTGCTGCCCGGGCTGG
Seq A exon
TGGAGACCTTTGGCGACTTGGCCTTTGGCGACATCTTCCTCCACCTGCTCACGGGCAACCTTGCGCTGCTGGCCGACGAATTTGCCCTTGAGGACTTCTGCAGCAGCCTCTTCGATGGCTTCTTCCTCACCGCCTCTCCAAG
Seq C2 exon
GAAGGAGAACGTGCACCGGCACGCGCTGCGGCTCCTCATTCACCTGCACCCCAGGGTGGCCCCGTCTAAGCTGGAGGCGTTGCAGAAGGCCCTGGAGCCTACAGGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188986-'10-11,'10-10,13-11=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.162
Domain overlap (PFAM):
C1:
PF062098=COBRA1=FE(7.6=100),PF069126=DUF1275=PU(19.6=29.7)
A:
PF062098=COBRA1=FE(9.9=100),PF069126=DUF1275=PD(78.6=91.7)
C2:
PF062098=COBRA1=FE(7.6=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCGAGGTGGGGCTGTACTA
R:
CTCCAGGGCCTTCTGCAAC
Band lengths:
178-320
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)