HsaEX6065080 @ hg38
Exon Skipping
Gene
ENSG00000175899 | A2M
Description
alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]
Coordinates
chr12:9072359-9074783:-
Coord C1 exon
chr12:9074011-9074783
Coord A exon
chr12:9072653-9072721
Coord C2 exon
chr12:9072359-9072486
Length
69 bp
Sequences
Splice sites
3' ss Seq
ACCGCCTGTTACTGCAGCAGGTC
3' ss Score
5.14
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
Exon sequences
Seq C1 exon
TTGAATGAAAAAGAAACAAACACATCCAAGAAGAAAAAAATACAGATGACAGTAACTTGAAATGAGGAAAAGTTTTCAGTATCCAAGGATAATGGAAATAAAAGCAAATCAAAGTCAAAGAGGGCCAAAAGGAAATGCTCAGAATCCCGGCACCCCATCGCTGTGTTATTATCCATCTCCTATTTCCCATAACAACACTGCCTTCCTCAAGCAGCAGTGGAGCACCAGCAGAATGAAGGAGATGTCTCCTGCCATTCTCCTGAAAGCTCTAGGGTCTCTTTCAAACTGTTCAAAGGAACTCTACTCAAAATCCAACAACCTCTCCTCGCAAATCTCTCCATTCTTAGGTCCCCTTTAATAGGCTTTTCTCAAAACTACACATTTTGTGCTTCCCCTATTCACCTTTTTTTTTTTTTTTTTTTTAAGACAGAGTCTTGCTCTGTCACCTAGGCTGGAATGCAGTGGTGCAATCTCGGCTCACTGCAACCTCCATCTCCCAG
Seq A exon
GTCTCATTGCCAGAGCTGCCTGGGGAATACAGCATGAAAGTGACAGGAGAAGGATGTGTCTACCTCCAG
Seq C2 exon
ACATCCTTGAAATACAATATTCTCCCAGAAAAGGAAGAGTTCCCCTTTGCTTTAGGAGTGCAGACTCTGCCTCAAACTTGTGATGAACCCAAAGCCCACACCAGCTTCCAAATCTCCCTAAGTGTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175899-'75-68,'75-67,76-68
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=0.267 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(28.8=100)
A:
PF076789=A2M_comp=PD(5.1=17.8)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTAGGCTGGAATGCAGTGGTG
R:
AGATTTGGAAGCTGGTGTGGG
Band lengths:
169-238
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains