HsaEX6075438 @ hg38
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65906085-65915598:-
Coord C1 exon
chr15:65915470-65915598
Coord A exon
chr15:65913737-65913973
Coord C2 exon
chr15:65906085-65906141
Length
237 bp
Sequences
Splice sites
3' ss Seq
GGCCCTCCCTCTGCCCGCAGCTG
3' ss Score
11.76
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
Exon sequences
Seq C1 exon
GATGTGCCCCAGGAACCTTTGGCTATGGGTGTCAGCAGCTATGTGAGTGCATGAACAACTCCACCTGTGACCATGTCACCGGCACCTGTTACTGCAGCCCTGGCTTCAAAGGAATCAGGTGTGACCAAG
Seq A exon
CTGCCCTCATGATGGAGGAGCTGAATCCCTACACCAAGATCAGCCCAGCACTGGGTGCAGAGCGGCACTCGGTGGGTGCTGTCACAGGCATCATGCTCCTGTTATTCCTCATTGTGGTGCTGCTGGGCCTATTTGCCTGGCATCGGCGGCGGCAGAAAGAGAAGGGCCGAGACCTGGCTCCCCGTGTCTCCTACACACCTGCCATGAGGATGACCAGCACCGACTACTCCCTCTCAG
Seq C2 exon
GTGCTTGTGGAATGGATAGACGTCAGAACACATACATTATGGACAAAGGCTTCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-'42-59,'42-50,43-59=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.025 A=0.071 C2=0.142
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(34.8=36.4),PF0005319=Laminin_EGF=PU(78.4=65.9)
A:
PF0005319=Laminin_EGF=PD(18.9=8.8)
C2:
NO
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGTGCCCCAGGAACCTTTG
R:
AGCCTTTGTCCATAATGTATGTGT
Band lengths:
180-417
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains