HsaEX6076317 @ hg38
Exon Skipping
Gene
ENSG00000181026 | AEN
Description
apoptosis enhancing nuclease [Source:HGNC Symbol;Acc:HGNC:25722]
Coordinates
chr15:88626146-88632282:+
Coord C1 exon
chr15:88626146-88626749
Coord A exon
chr15:88629226-88629426
Coord C2 exon
chr15:88630058-88632282
Length
201 bp
Sequences
Splice sites
3' ss Seq
ACTCCTCTTTCTGCTCACAGATC
3' ss Score
11.64
5' ss Seq
CAGGTGCGT
5' ss Score
9.73
Exon sequences
Seq C1 exon
GCCCTTCCCTCACCATCCCAAATGCCAAGGATGTGCTTCGGAAGAGGCACAAGAGAAGGAGCCGACAGCACCAGCGGTTCATGGCCCGGAAGGCCTTGCTGCAGGAGCAGGGGCTGCTGAGCATGCCTCCAGAACCAGGGTCCTCCCCACTGCCCACCCCTTTCGGGGCAGCGACAGCAACTGAAGCTGCCAGCAGTGGGAAGCAGTGTCTGAGGGCTGGATCTGGCAGTGCCCCATGCAGCAGAAGGCCTGCTCCCGGGAAAGCCTCAGGGCCCTTGCCCAGCAAGTGTGTGGCTATCGACTGTGAGATGGTGGGCACGGGACCCCGAGGGCGGGTAAGCGAGCTGGCCCGCTGTTCCATTGTGAGCTACCATGGCAATGTCCTCTATGACAAGTACATCAGGCCTGAGATGCCCATCGCTGACTACCGTACCCGCTGGAGTGGCATCACTCGGCAGCACATGCGCAAGGCTGTCCCCTTCCAGGTGGCCCAGAAAGAG
Seq A exon
ATCCTTAAGCTCCTGAAGGGCAAGGTGGTGGTGGGGCACGCGCTGCACAACGACTTCCAGGCGCTCAAGTATGTCCACCCTCGGAGCCAGACCCGGGATACGACCTATGTCCCAAACTTCCTCAGCGAGCCCGGCCTCCACACCCGGGCCCGGGTCTCTCTAAAGGACCTGGCCCTGCAGCTGCTGCACAAGAAGATCCAG
Seq C2 exon
GTGGGCCAGCACGGGCACTCATCAGTAGAAGATGCCACGACAGCCATGGAGCTCTACCGGCTGGTGGAGGTGCAGTGGGAACAGCAGGAGGCCCGCAGCCTCTGGACCTGCCCCGAGGACAGAGAACCTGACAGCAGCACAGACATGGAACAGTACATGGAGGACCAGTACTGGCCCGATGACCTGGCCCACGGCAGCAGAGGAGGAGCCAGGGAGGCACAGGACAGAAGGAATTGAGAAGGGGGCGGGGCTCCCTGGCTGGGCTTCCGGTGTGGCCGGTAGGAAGTGGGGGCCAGGAGAGCAGCGGGCACTCCTTCCTGGGCAGGGTGGGGCAGGATGCAGTGAGCCAGCCCCAGGGCCAGAGGAGTAGGGGTCATCTGTTACCTTGACACCCTCTGCACACAGCATAGCCCTCTCTCTCTCCAGGGCTGTTGGTTCTTTCTTCTGACTCCTGTGGTTTTGCTAATGGCACTTTACAGACTCCATGGAGATGTCAGGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000181026-'11-5,'11-3,14-5
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.428 A=0.075 C2=0.679
Domain overlap (PFAM):
C1:
PF0092919=RNase_T=PU(44.2=38.3)
A:
PF0092919=RNase_T=FE(42.3=100)
C2:
PF0092919=RNase_T=PD(11.5=22.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCATTGTGAGCTACCATGGCA
R:
CTGTTCCATGTCTGTGCTGCT
Band lengths:
296-497
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains