HsaEX6076334 @ hg38
Exon Skipping
Gene
ENSG00000140545 | MFGE8
Description
milk fat globule-EGF factor 8 protein [Source:HGNC Symbol;Acc:HGNC:7036]
Coordinates
chr15:88906626-88909923:-
Coord C1 exon
chr15:88909792-88909923
Coord A exon
chr15:88907195-88907376
Coord C2 exon
chr15:88906626-88906778
Length
182 bp
Sequences
Splice sites
3' ss Seq
TGCCACCTCCCTTCCCTCAGAAT
3' ss Score
9.87
5' ss Seq
CAGGTATGC
5' ss Score
9.37
Exon sequences
Seq C1 exon
ATATCTGTTCCAAAAACCCCTGCCACAACGGTGGTTTATGCGAGGAGATTTCCCAAGAAGTGCGAGGAGATGTCTTCCCCTCGTACACCTGCACGTGCCTTAAGGGCTACGCGGGCAACCACTGTGAGACGA
Seq A exon
AATGTGTCGAGCCACTGGGCCTGGAGAATGGGAACATTGCCAACTCACAGATCGCCGCCTCGTCTGTGCGTGTGACCTTCTTGGGTTTGCAGCATTGGGTCCCGGAGCTGGCCCGCCTGAACCGCGCAGGCATGGTCAATGCCTGGACACCCAGCAGCAATGACGATAACCCCTGGATCCAG
Seq C2 exon
GTGAACCTGCTGCGGAGGATGTGGGTAACAGGTGTGGTGACGCAGGGTGCCAGCCGCTTGGCCAGTCATGAGTACCTGAAGGCCTTCAAGGTGGCCTACAGCCTTAATGGACACGAATTCGATTTCATCCATGATGTTAATAAAAAACACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000140545-'8-18,'8-16,16-18=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.020 C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=WD(100=86.7)
A:
PF0075420=F5_F8_type_C=PU(31.9=72.1)
C2:
PF0075420=F5_F8_type_C=PU(18.9=83.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTGTTCCAAAAACCCCTGCC
R:
CGTGTCCATTAAGGCTGTAGGC
Band lengths:
244-426
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains