HsaEX6077033 @ hg19
Exon Skipping
Gene
ENSG00000101224 | CDC25B
Description
cell division cycle 25 homolog B (S. pombe) [Source:HGNC Symbol;Acc:1726]
Coordinates
chr20:3780935-3781512:+
Coord C1 exon
chr20:3780935-3780976
Coord A exon
chr20:3781109-3781145
Coord C2 exon
chr20:3781390-3781512
Length
37 bp
Sequences
Splice sites
3' ss Seq
GTCCCCATTTCCTCCTGTAGCGA
3' ss Score
8.4
5' ss Seq
CCGGTGAGT
5' ss Score
10.9
Exon sequences
Seq C1 exon
GTTTGAACAGGCCATCCAGGCAGCCAGCCGGATCATTCGAAA
Seq A exon
CGAGCAGTTTGCCATCAGACGCTTCCAGTCTATGCCG
Seq C2 exon
GTGAGGCTGCTGGGCCACAGCCCCGTGCTTCGGAACATCACCAACTCCCAGGCGCCCGACGGCCGGAGGAAGAGCGAGGCGGGCAGTGGAGCTGCCAGCAGCTCTGGGGAAGACAAGGAGAAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000101224-'5-9,'5-8,6-9=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.433 A=0.000 C2=0.773
Domain overlap (PFAM):
C1:
PF066178=M-inducer_phosp=FE(33.3=100)
A:
PF066178=M-inducer_phosp=FE(28.6=100),PF066178=M-inducer_phosp=PU(0.1=0.0)
C2:
PF066178=M-inducer_phosp=FE(14.7=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTTGAACAGGCCATCCAGG
R:
CTCTTCCTCCGGCCGTCG
Band lengths:
116-153
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)