HsaEX6082158 @ hg19
Exon Skipping
Gene
ENSG00000187955 | COL14A1
Description
collagen, type XIV, alpha 1 [Source:HGNC Symbol;Acc:2191]
Coordinates
chr8:121174665-121209185:+
Coord C1 exon
chr8:121174665-121174808
Coord A exon
chr8:121180400-121180486
Coord C2 exon
chr8:121209030-121209185
Length
87 bp
Sequences
Splice sites
3' ss Seq
TATCTCTACTTTTCTTCCAGTTA
3' ss Score
8.63
5' ss Seq
AAGGTCAGA
5' ss Score
6.8
Exon sequences
Seq C1 exon
GTGGAAAAACTAACCAGCTGAATCTGCAGAACACTGCAACTAAAGCAATTATTCAAGGCCTTATGCCAGACCAGAATTACACAGTTCAAATTATTGCATACAATAAAGATAAAGAAAGCAAGCCAGCTCAAGGCCAATTCAGAA
Seq A exon
TTAAAGATTTAGAAAAAAGAAAGGATCCAAAGCCCAGAGTCAAAGTTGTGGACAGAGGAAATGGGAGTAGACCATCTTCACCAGAAG
Seq C2 exon
AAGTGAAATTTGTCTGTCAAACTCCAGCAATTGCTGACATTGTAATCCTGGTCGATGGTTCATGGAGTATTGGAAGATTCAACTTCAGACTGGTTCGGCATTTCTTGGAAAACCTGGTTACAGCATTCGATGTGGGCTCAGAGAAGACACGAATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187955-'8-11,'8-10,9-11=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.163 A=0.767 C2=0.018
Domain overlap (PFAM):
C1:
PF0004116=fn3=PD(51.9=85.7)
A:
NO
C2:
PF0009223=VWA=PU(95.2=75.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGCTCAAGGCCAATTCAGA
R:
TTCGTGTCTTCTCTGAGCCCA
Band lengths:
175-262
Functional annotations
There are 1 annotated functions for this event
PMID: 11098058
Alternative splicing of the first F3 domain from chicken collagen XIV affects cell adhesion and heparin binding.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)