MmuEX6053676 @ mm10
Exon Skipping
Gene
ENSMUSG00000022371 | Col14a1
Description
collagen, type XIV, alpha 1 [Source:MGI Symbol;Acc:MGI:1341272]
Coordinates
chr15:55341681-55362537:+
Coord C1 exon
chr15:55341681-55341824
Coord A exon
chr15:55344870-55344959
Coord C2 exon
chr15:55362382-55362537
Length
90 bp
Sequences
Splice sites
3' ss Seq
TTTCTTTCCTTTTCTTCTAGTTA
3' ss Score
10.06
5' ss Seq
AAGGTCAGA
5' ss Score
6.8
Exon sequences
Seq C1 exon
GAGGAAAGACCAACCAGATGAATCTCCAGAACACTGCAACAAAAGCGATTATTCAAGGCCTTCTGCCAGAGCAGAACTACACAGTTCAACTCATTGCCTACTATAAAGACAAGGAAAGCAAGCCCGCTCAAGGCCAGTTCAGAA
Seq A exon
TTAAAGATTTAGAGAAAAGAAAGGATCCAACAAAGCCCAAAGTCAAGGTTGTGGACAAAGGAAATGGAAGTAAACCAACTTCACCAGAAG
Seq C2 exon
AGGTAAAATTCTTCTGTGAGACTCCAGCCATCGCTGACATCGTCATCCTGGTGGATGGGTCGTGGAGTATTGGGAGGTTCAACTTCAGGCTTGTGCGCAATTTCTTGGAAAACCTGGTCACAGCGTTCAACGTGGGCTCAGAAAAGACAAGAATCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022371-'1-6,'1-5,4-6=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.102 A=0.613 C2=0.000
Domain overlap (PFAM):
C1:
PF0004116=fn3=PD(51.9=85.7)
A:
NO
C2:
PF0009223=VWA=PU(23.1=75.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGACAAGGAAAGCAAGCCCG
R:
TGAACGCTGTGACCAGGTTTT
Band lengths:
168-258
Functional annotations
There are 1 annotated functions for this event
PMID: 11098058
This event
Alternative splicing of the first F3 domain from chicken collagen XIV affects cell adhesion and heparin binding.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types