Special

MmuEX6053677 @ mm10

Exon Skipping

Gene
Description
collagen, type XIV, alpha 1 [Source:MGI Symbol;Acc:MGI:1341272]
Coordinates
chr15:55338406-55344959:+
Coord C1 exon
chr15:55338406-55338522
Coord A exon
chr15:55341681-55341824
Coord C2 exon
chr15:55344870-55344959
Length
144 bp
Sequences
Splice sites
3' ss Seq
GTCGTTCTGTTTTATTACAGGAG
3' ss Score
9.03
5' ss Seq
GAAGTATGT
5' ss Score
6.97
Exon sequences
Seq C1 exon
TGGCTCCACCCACAAGGTTAAGATATAATGTGATTTCCCATGATAGTATACAGATTTCATGGAAAGCACCAAGAGGGAAATTTGGTGGCTACAAACTGCTCGTGGCTCCAGCTTCAG
Seq A exon
GAGGAAAGACCAACCAGATGAATCTCCAGAACACTGCAACAAAAGCGATTATTCAAGGCCTTCTGCCAGAGCAGAACTACACAGTTCAACTCATTGCCTACTATAAAGACAAGGAAAGCAAGCCCGCTCAAGGCCAGTTCAGAA
Seq C2 exon
TTAAAGATTTAGAGAAAAGAAAGGATCCAACAAAGCCCAAAGTCAAGGTTGTGGACAAAGGAAATGGAAGTAAACCAACTTCACCAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022371-'1-6,'1-4,3-6=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.102 C2=0.613
Domain overlap (PFAM):

C1:
PF0004116=fn3=PU(46.9=95.0)
A:
PF0004116=fn3=PD(51.9=85.7)
C2:
NO


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
ALTERNATIVE
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCACAAGGTTAAGATATAATGTGAT
R:
TGGTTTACTTCCATTTCCTTTGTCCA
Band lengths:
186-330
Functional annotations
There are 2 annotated functions for this event
PMID: 11098058
This event
Alternative splicing of the first F3 domain from chicken collagen XIV affects cell adhesion and heparin binding.
PMID: 11098058
Alternative splicing of the first F3 domain from chicken collagen XIV affects cell adhesion and heparin binding.


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types