HsaEX6083084 @ hg19
Exon Skipping
Gene
ENSG00000133256 | PDE6B
Description
phosphodiesterase 6B, cGMP-specific, rod, beta [Source:HGNC Symbol;Acc:8786]
Coordinates
chr4:656298-657659:+
Coord C1 exon
chr4:656298-656407
Coord A exon
chr4:656889-656976
Coord C2 exon
chr4:657559-657659
Length
88 bp
Sequences
Splice sites
3' ss Seq
CTCCACCACCTGTGTAACAGGTC
3' ss Score
6.56
5' ss Seq
GAGGTTGGT
5' ss Score
6.36
Exon sequences
Seq C1 exon
ACCGGCAAACTGAAGAGCTACTACACGGACCTGGAGGCCTTCGCCATGGTGACAGCCGGCCTGTGCCATGACATCGACCACCGCGGCACCAACAACCTGTACCAGATGAA
Seq A exon
GTCCCAGAACCCCTTGGCTAAGCTCCACGGCTCCTCGATTTTGGAGCGGCACCACCTGGAGTTTGGGAAGTTCCTGCTCTCGGAGGAG
Seq C2 exon
ACCCTGAACATCTACCAGAACCTGAACCGGCGGCAGCACGAGCACGTGATCCACCTGATGGACATCGCCATCATCGCCACGGACCTGGCCCTGTACTTCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133256-'24-23,'24-21,25-23=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(14.5=100),PF0771711=OB_NTP_bind=PU(18.6=70.3)
A:
PF0023314=PDEase_I=FE(11.6=100),PF0771711=OB_NTP_bind=FE(20.7=100)
C2:
PF0023314=PDEase_I=FE(13.3=100),PF0771711=OB_NTP_bind=FE(23.6=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCTACTACACGGACCTGGAG
R:
GATGGCGATGTCCATCAGGTG
Band lengths:
167-255
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)