HsaEX6087210 @ hg38
Exon Skipping
Gene
ENSG00000088926 | F11
Description
coagulation factor XI [Source:HGNC Symbol;Acc:HGNC:3529]
Coordinates
chr4:186280474-186285813:+
Coord C1 exon
chr4:186280474-186280580
Coord A exon
chr4:186284092-186284260
Coord C2 exon
chr4:186285638-186285813
Length
169 bp
Sequences
Splice sites
3' ss Seq
TCACAATGCTTCTGTTGCAGAGT
3' ss Score
8.11
5' ss Seq
TGGGTCAGT
5' ss Score
4.68
Exon sequences
Seq C1 exon
GGGCAAGTGTTACTTAAAGCTTTCTTCAAACGGATCTCCAACTAAAATACTTCACGGGAGAGGAGGCATCTCTGGATACACATTAAGGTTGTGTAAAATGGATAATG
Seq A exon
AGTGTACCACCAAAATCAAGCCCAGGATCGTTGGAGGAACTGCGTCTGTTCGTGGTGAGTGGCCGTGGCAGGTGACCCTGCACACAACCTCACCCACTCAGAGACACCTGTGTGGAGGCTCCATCATTGGAAACCAGTGGATATTAACAGCCGCTCACTGTTTCTATGG
Seq C2 exon
GGTAGAGTCACCTAAGATTTTGCGTGTCTACAGTGGCATTTTAAATCAATCTGAAATAAAAGAGGACACATCTTTCTTTGGGGTTCAAGAAATAATAATCCATGATCAGTATAAAATGGCAGAAAGCGGGTATGATATTGCCTTGTTGAAACTGGAAACCACAGTGAATTACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000088926-'16-22,'16-21,24-22=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF142951=PAN_4=PD(11.8=16.2)
A:
PF0008921=Trypsin=PU(20.3=82.5)
C2:
PF0008921=Trypsin=FE(25.5=100)
Main Skipping Isoform:
ENST00000403665fB2485
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCTTTCTTCAAACGGATCTCCA
R:
GTGGTTTCCAGTTTCAACAAGGC
Band lengths:
252-421
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains