HsaEX6087806 @ hg38
Exon Skipping
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 [Source:HGNC Symbol;Acc:HGNC:16063]
Coordinates
chr10:21534645-21586348:+
Coord C1 exon
chr10:21534645-21534804
Coord A exon
chr10:21538833-21538912
Coord C2 exon
chr10:21586294-21586348
Length
80 bp
Sequences
Splice sites
3' ss Seq
CACATTTCATTTTTCAACAGCTT
3' ss Score
7.9
5' ss Seq
GTGGTAAGG
5' ss Score
8.37
Exon sequences
Seq C1 exon
ATGGTCTCTAGCGACCGGCCCGTGTCACTGGAGGACGAGGTCTCCCATAGTATGAAGGAGATGATTGGAGGCTGTTGCGTTTGCTCAGACGAGAGAGGCTGGGCCGAGAACCCGCTGGTTTATTGCGACGGGCACGGCTGCAGCGTCGCGGTGCATCAAG
Seq A exon
CTTGCTATGGCATTGTTCAAGTACCCACTGGACCGTGGTTTTGCAGGAAATGTGAATCTCAGGAGAGAGCAGCCAGAGTG
Seq C2 exon
AGATGTGAACTTTGTCCCCATAAGGATGGAGCTTTAAAAAGAACAGATAATGGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403-'3-31,'3-9,16-31
Average complexity
C2
Mappability confidence:
95%=94=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.037 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF138311=PHD_2=PU(48.6=33.3)
A:
PF138311=PHD_2=PD(48.6=66.7),PF138321=zf-HC5HC2H_2=PU(0.1=0.0)
C2:
PF138321=zf-HC5HC2H_2=FE(15.3=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAGGACGAGGTCTCCCATAG
R:
TCTGTTCTTTTTAAAGCTCCATCCT
Band lengths:
178-258
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains