MmuEX0029210 @ mm10
Exon Skipping
Gene
ENSMUSG00000026743 | Mllt10
Description
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 [Source:MGI Symbol;Acc:MGI:1329038]
Coordinates
chr2:18065035-18122348:+
Coord C1 exon
chr2:18065035-18065194
Coord A exon
chr2:18071125-18071204
Coord C2 exon
chr2:18122245-18122348
Length
80 bp
Sequences
Splice sites
3' ss Seq
TTCTTTTTGTTTCCTAACAGCTT
3' ss Score
10.84
5' ss Seq
GTGGTAAGG
5' ss Score
8.37
Exon sequences
Seq C1 exon
ATGGTCTCTAGCGACCGGCCCGTGTCACTGGAGGACGAGGTCTCCCATAGTATGAAGGAAATGATTGGAGGCTGTTGCGTTTGCTCAGACGAGAGAGGCTGGGCCGAGAACCCGCTGGTTTATTGCGACGGGCACGGCTGCAGCGTCGCGGTGCATCAAG
Seq A exon
CTTGCTATGGCATTGTTCAAGTACCTACTGGACCGTGGTTTTGTAGGAAATGTGAATCTCAGGAGAGAGCAGCCAGAGTG
Seq C2 exon
ACTTGCTATATATGTGATGAACAAGGACGAGAAAGCAAAGCAGCCACTGGTGCTTGCATGACATGTAATAAACATGGATGTCGACAGGCTTTCCATGTAACATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026743_MULTIEX1-2/20=C1-10
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.062 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF138311=PHD_2=PU(48.6=33.3)
A:
PF138311=PHD_2=PD(48.6=66.7),PF138321=zf-HC5HC2H_2=PU(0.1=0.0)
C2:
PF138321=zf-HC5HC2H_2=FE(28.8=100)
Main Skipping Isoform:
ENSMUST00000114671fB2483
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATGATTGGAGGCTGTTGCGT
R:
ACATGTCATGCAAGCACCAGT
Band lengths:
167-247
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types