Special

MmuEX0029222 @ mm10

Exon Skipping

Gene
Description
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 [Source:MGI Symbol;Acc:MGI:1329038]
Coordinates
chr2:18071125-18109891:+
Coord C1 exon
chr2:18071125-18071204
Coord A exon
chr2:18101458-18101512
Coord C2 exon
chr2:18109782-18109891
Length
55 bp
Sequences
Splice sites
3' ss Seq
TTTTAATTTTCTTTAAATAGAGA
3' ss Score
6.88
5' ss Seq
GGGGTAAGT
5' ss Score
9.65
Exon sequences
Seq C1 exon
CTTGCTATGGCATTGTTCAAGTACCTACTGGACCGTGGTTTTGTAGGAAATGTGAATCTCAGGAGAGAGCAGCCAGAGTG
Seq A exon
AGATGTGAGCTGTGTCCCCATAAAGATGGAGCTTTAAAAAGAACAGATAATGGGG
Seq C2 exon
GTTGGGCTCATGTGGTTTGTGCCCTCTATATTCCAGAGGTACAATTTGCCAATGTTTCTACAATGGAGCCAATCGTTTTACAGTCTGTCCCACATGATCGTTATAATAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026743_MULTIEX1-6/20=2-8
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

Show structural model
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF138311=PHD_2=PD(48.6=66.7),PF138321=zf-HC5HC2H_2=PU(0.1=0.0)
A:
PF138321=zf-HC5HC2H_2=FE(15.3=100)
C2:
PF138321=zf-HC5HC2H_2=FE(30.5=100)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Other assemblies
Conservation
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTGGACCGTGGTTTTGTAGG
R:
TGTGGGACAGACTGTAAAACGA
Band lengths:
148-203
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types