Special

MmuEX0029224 @ mm10

Exon Skipping

Gene
Description
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 [Source:MGI Symbol;Acc:MGI:1329038]
Coordinates
chr2:18109782-18146872:+
Coord C1 exon
chr2:18109782-18109891
Coord A exon
chr2:18122245-18122348
Coord C2 exon
chr2:18146777-18146872
Length
104 bp
Sequences
Splice sites
3' ss Seq
TCTTGTTTCTTTCTCCCAAGACT
3' ss Score
6.96
5' ss Seq
ATGGTATGT
5' ss Score
8.35
Exon sequences
Seq C1 exon
GTTGGGCTCATGTGGTTTGTGCCCTCTATATTCCAGAGGTACAATTTGCCAATGTTTCTACAATGGAGCCAATCGTTTTACAGTCTGTCCCACATGATCGTTATAATAAG
Seq A exon
ACTTGCTATATATGTGATGAACAAGGACGAGAAAGCAAAGCAGCCACTGGTGCTTGCATGACATGTAATAAACATGGATGTCGACAGGCTTTCCATGTAACATG
Seq C2 exon
AAATATAAAGAAAAGGACAAACACAAACAAAAACACAAGAAGCAACCAGAACCGTCACCTGCCTTGGTTCCTTCTTTGACTGTTACTACAGAAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026743_MULTIEX1-10/20=8-14
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.955
Domain overlap (PFAM):

C1:
PF138321=zf-HC5HC2H_2=FE(30.5=100)
A:
PF138321=zf-HC5HC2H_2=FE(28.8=100)
C2:
PF105004=SR-25=PD(26.9=65.6)


Main Inclusion Isoform:


Main Skipping Isoform:
ENSMUST00000114671fB12916


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Other assemblies
Conservation
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTGGGCTCATGTGGTTTGTG
R:
AACAGTCAAAGAAGGAACCAAGGC
Band lengths:
194-298
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types