Special

MmuEX0029226 @ mm10

Exon Skipping

Gene
Description
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 [Source:MGI Symbol;Acc:MGI:1329038]
Coordinates
chr2:18123719-18146872:+
Coord C1 exon
chr2:18123719-18123812
Coord A exon
chr2:18126134-18126229
Coord C2 exon
chr2:18146777-18146872
Length
96 bp
Sequences
Splice sites
3' ss Seq
GTATATATTTTCTTTTTTAGAAA
3' ss Score
9.96
5' ss Seq
AAAGTAAGT
5' ss Score
9.72
Exon sequences
Seq C1 exon
TGCTCAGTTTGCCGGGCTGCTTTGTGAAGAAGAAGGGAATGGCGCAGACAATGTTCAATACTGTGGCTACTGTAAATACCACTTTAGTAAGCTG
Seq A exon
AAAAAGAGCAAACGGGGATCTAATAGGTCATATGAGCAAAGTTTAAGTGACTCTTCCTCTCACTCTCAGGATAAGCATCATGAGAAAGAGAAAAAA
Seq C2 exon
AAATATAAAGAAAAGGACAAACACAAACAAAAACACAAGAAGCAACCAGAACCGTCACCTGCCTTGGTTCCTTCTTTGACTGTTACTACAGAAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026743-'26-49,'26-33,28-49
Average complexity
C1
Mappability confidence:
91%=100=88%
Protein Impact

Alternative protein isoforms (Ref)

Show structural model
Features
Disorder rate (Iupred):
  C1=0.000 A=0.839 C2=0.955
Domain overlap (PFAM):

C1:
PF138321=zf-HC5HC2H_2=PD(22.9=84.4),PF105004=SR-25=PU(29.5=71.9)
A:
PF105004=SR-25=FE(39.7=100)
C2:
PF105004=SR-25=PD(26.9=65.6)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Other assemblies
Conservation
Chicken
(galGal4)
ALTERNATIVE
Chicken
(galGal3)
ALTERNATIVE
Zebrafish
(danRer10)
ALTERNATIVE
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTTTGCCGGGCTGCTTTG
R:
CAAAGAAGGAACCAAGGCAGGT
Band lengths:
167-263
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types