HsaEX0039537 @ hg19
Exon Skipping
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 [Source:HGNC Symbol;Acc:16063]
Coordinates
chr10:21903760-21940697:+
Coord C1 exon
chr10:21903760-21903853
Coord A exon
chr10:21906041-21906136
Coord C2 exon
chr10:21940602-21940697
Length
96 bp
Sequences
Splice sites
3' ss Seq
ATATATATTTTCTTTTTTAGAAA
3' ss Score
10.16
5' ss Seq
AAAGTAAGT
5' ss Score
9.72
Exon sequences
Seq C1 exon
CGCTCAGTTTGCCGGACTGCTTTGTGAAGAAGAAGGTAATGGTGCCGATAATGTCCAATACTGTGGCTACTGTAAATACCATTTTAGTAAGCTG
Seq A exon
AAAAAGAGCAAACGGGGATCTAATAGGTCATATGATCAAAGTTTAAGTGATTCTTCCTCTCACTCTCAGGATAAACATCATGAGAAAGAGAAAAAA
Seq C2 exon
AAATATAAAGAGAAGGACAAACACAAACAGAAACACAAGAAGCAGCCAGAACCATCACCTGCATTGGTTCCATCCTTGACTGTTACTACAGAAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.841 C2=0.994
Domain overlap (PFAM):
C1:
PF138321=zf-HC5HC2H_2=PD(22.9=84.4),PF105004=SR-25=PU(30.7=71.9)
A:
PF105004=SR-25=FE(41.3=100)
C2:
PF105004=SR-25=PD(24.0=56.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCAGTTTGCCGGACTGCTTT
R:
AGGATGGAACCAATGCAGGTG
Band lengths:
168-264
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)