HsaEX6088045 @ hg38
Exon Skipping
Gene
ENSG00000148516 | ZEB1
Description
zinc finger E-box binding homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11642]
Coordinates
chr10:31510673-31521936:+
Coord C1 exon
chr10:31510673-31510875
Coord A exon
chr10:31514603-31514708
Coord C2 exon
chr10:31520126-31521936
Length
106 bp
Sequences
Splice sites
3' ss Seq
TACCAGTTCTTTTCTTACAGAGA
3' ss Score
7.31
5' ss Seq
GTGGTAAAT
5' ss Score
5.18
Exon sequences
Seq C1 exon
GAACACCAGATGCATTTTCACAATTACTCACCTGTCCATATTGTGATAGAGGCTATAAACGCTTTACCTCTCTGAAAGAACACATTAAATATCGTCATGAAAAGAATGAAGATAACTTTAGTTGCTCCCTGTGCAGTTACACCTTTGCATACAGAACCCAACTTGAACGTCACATGACATCACATAAATCAGGAAGAGATCAA
Seq A exon
AGACATGTGACGCAGTCTGGGTGTAATCGTAAATTCAAATGCACTGAGTGTGGAAAAGCTTTCAAATACAAACATCACCTAAAAGAGCACTTAAGAATTCACAGTG
Seq C2 exon
GAGAGAAGCCATATGAATGCCCAAACTGCAAGAAACGCTTTTCCCATTCTGGCTCCTATAGCTCACACATAAGCAGTAAGAAATGTATCAGCTTGATACCTGTGAATGGGCGACCAAGAACAGGACTCAAGACATCTCAGTGTTCTTCACCGTCTCTTTCAGCATCACCAGGCAGTCCCACACGACCACAGATACGGCAAAAGATAGAGAATAAACCCCTTCAAGAACAACTTTCTGTTAACCAAATTAAAACTGAACCTGTGGATTATGAATTCAAACCCATAGTGGTTGCTTCAGGAATCAACTGTTCAACCCCTTTACAAAATGGGGTTTTCACTGGTGGTGGCCCATTACAGGCAACCAGTTCTCCTCAGGGCATGGTGCAAGCTGTTGTTCTGCCAACAGTTGGTTTGGTGTCTCCCATAAGTATCAATTTAAGTGATATTCAGAATGTACTTAAAGTGGCGGTAGATGGTAATGTAATAAGGCAAGTGTTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000148516-'58-78,'58-73,65-78
Average complexity
C1
Mappability confidence:
100%=100=86%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.233 A=0.093 C2=0.494
Domain overlap (PFAM):
C1:
PF056057=zf-Di19=WD(100=83.8)
A:
PF134651=zf-H2C2_2=PU(38.5=27.8)
C2:
PF134651=zf-H2C2_2=PD(57.7=2.5),PF0004624=Homeobox=WD(100=8.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGCTCCCTGTGCAGTTACAC
R:
ACTGCCTGGTGATGCTGAAAG
Band lengths:
258-364
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains