HsaEX6090182 @ hg38
Exon Skipping
Gene
ENSG00000148795 | CYP17A1
Description
cytochrome P450 family 17 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2593]
Coordinates
chr10:102832993-102837533:-
Coord C1 exon
chr10:102837065-102837533
Coord A exon
chr10:102834785-102835014
Coord C2 exon
chr10:102832993-102833208
Length
230 bp
Sequences
Splice sites
3' ss Seq
CATGCCCCCTCTCCCTTCAGTTT
3' ss Score
12.14
5' ss Seq
AAGGTGAGA
5' ss Score
8.68
Exon sequences
Seq C1 exon
ATATGAGCTCAGGCCTGGCTGGGCTCCAGGAGAATCTTTCCACAAGGCAAGAGATAACACAAAGTCAAGGTGAAGATCAGGGTAGCCCTTTAAAAGGCCTCCTTGTGCCCTAGAGTTGCCACAGCTCTTCTACTCCACTGCTGTCTATCTTGCCTGCCGGCACCCAGCCACCATGTGGGAGCTCGTGGCTCTCTTGCTGCTTACCCTAGCTTATTTGTTTTGGCCCAAGAGAAGGTGCCCTGGTGCCAAGTACCCCAAGAGCCTCCTGTCCCTGCCCCTGGTGGGCAGCCTGCCATTCCTCCCCAGACACGGCCATATGCATAACAACTTCTTCAAGCTGCAGAAAAAATATGGCCCCATCTATTCGGTTCGTATGGGCACCAAGACTACAGTGATTGTCGGCCACCACCAGCTGGCCAAGGAGGTGCTTATTAAGAAGGGCAAGGACTTCTCTGGGCGGCCTCAAATG
Seq A exon
TTTGTCAGGAAATCAGTACATTGTGTGATATGCTGGCCACCCACAACGGACAGTCCATAGACATCTCCTTTCCTGTCTTCGTGGCGGTAACCAATGTCATCTCCTTGATCTGCTTCAATACCTCCTACAAGAATGGGGACCCTGAGTTGAATGTCATACAGAATTACAATGAAGGCATCATAGACAACCTGAGCAAAGACAGCCTGGTGGACCTAGTCCCCTGGTTGAAG
Seq C2 exon
GAGAAATTCCGGAGTGACTCTATCACCAACATGCTGGACACACTGATGCAAGCCAAGATGAACTCAGATAATGGCAATGCTGGCCCAGATCAAGACTCAGAGCTGCTTTCAGATAACCACATTCTCACCACCATAGGGGACATCTTTGGGGCTGGCGTGGAGACCACCACCTCTGTGGTTAAATGGACCCTGGCCTTCCTGCTGCACAATCCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000148795_MULTIEX1-2/4=C1-4
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.222
Domain overlap (PFAM):
C1:
PF0006717=p450=PU(15.2=71.7)
A:
PF0006717=p450=FE(38.6=100),PF0006717=p450=PU(0.6=1.3)
C2:
PF0006717=p450=PD(9.9=11.1),PF0006717=p450=PU(29.3=98.6)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGTACCCCAAGAGCCTCCTG
R:
GGGCCAGCATTGCCATTATCT
Band lengths:
308-538
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains