HsaEX6091578 @ hg19
Exon Skipping
Gene
ENSG00000185761 | ADAMTSL5
Description
ADAMTS-like 5 [Source:HGNC Symbol;Acc:27912]
Coordinates
chr19:1506589-1507404:-
Coord C1 exon
chr19:1507241-1507404
Coord A exon
chr19:1506738-1506927
Coord C2 exon
chr19:1506589-1506660
Length
190 bp
Sequences
Splice sites
3' ss Seq
TGTCCCCTCCCCTGCTCCAGGTC
3' ss Score
11.21
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
CACTGATGGGGGGCGATGGGCGCTACGTGCTTAATGGGCACTGGGTGGTCAGCCCACCAGGGACCTACGAGGCGGCCGGCACGCATGTGGTCTACACCCGAGACACAGGGCCCCAGGAGACATTGCAAGCAGCCGGGCCCACCTCCCATGACCTGCTCCTACAG
Seq A exon
GTCCTCCTGCAGGAGCCCAACCCTGGCATCGAGTTTGAGTTCTGGCTCCCTCGGGAGCGCTACAGCCCCTTCCAGGCTCGTGTGCAGGCCCTGGGCTGGCCCCTGAGGCAGCCTCAGCCCCGGGGGGTGGAGCCTCAGCCCCCCGCAGCCCCTGCTGTCACCCCTGCACAGACCCCAACGCTGGCCCCAG
Seq C2 exon
ACCCCTGCCCACCCTGCCCTGACACCCGCGGCCGCGCCCACCGACTACTCCACTATTGCGGCAGTGACTTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185761-'11-13,'11-12,12-13=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.431 A=0.527 C2=0.360
Domain overlap (PFAM):
C1:
PF059869=ADAM_spacer1=PU(73.9=96.2)
A:
PF059869=ADAM_spacer1=PD(14.5=25.0)
C2:
PF0175916=NTR=PU(7.7=32.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGGGCGCTACGTGCTTAAT
R:
CAAAGTCACTGCCGCAATAGTG
Band lengths:
222-412
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)