HsaEX6092290 @ hg19
Exon Skipping
Gene
ENSG00000125730 | C3
Description
complement component 3 [Source:HGNC Symbol;Acc:1318]
Coordinates
chr19:6718105-6719414:-
Coord C1 exon
chr19:6719222-6719414
Coord A exon
chr19:6718258-6718423
Coord C2 exon
chr19:6718105-6718175
Length
166 bp
Sequences
Splice sites
3' ss Seq
AATGCCCTGCCCACGCCTAGATC
3' ss Score
4.92
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
GTACTCTATCATCACCCCCAACATCTTGCGGCTGGAGAGCGAGGAGACCATGGTGCTGGAGGCCCACGACGCGCAAGGGGATGTTCCAGTCACTGTTACTGTCCACGACTTCCCAGGCAAAAAACTAGTGCTGTCCAGTGAGAAGACTGTGCTGACCCCTGCCACCAACCACATGGGCAACGTCACCTTCACG
Seq A exon
ATCCCAGCCAACAGGGAGTTCAAGTCAGAAAAGGGGCGCAACAAGTTCGTGACCGTGCAGGCCACCTTCGGGACCCAAGTGGTGGAGAAGGTGGTGCTGGTCAGCCTGCAGAGCGGGTACCTCTTCATCCAGACAGACAAGACCATCTACACCCCTGGCTCCACAG
Seq C2 exon
TTCTCTATCGGATCTTCACCGTCAACCACAAGCTGCTACCCGTGGGCCGGACGGTCATGGTCAACATTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125730-'3-6,'3-5,4-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0183514=A2M_N=PU(16.7=28.6)
C2:
PF0183514=A2M_N=FE(24.0=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCATCACCCCCAACATCTTGC
R:
AATGTTGACCATGACCGTCCG
Band lengths:
253-419
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)