HsaEX6092307 @ hg19
Exon Skipping
Gene
ENSG00000125730 | C3
Description
complement component 3 [Source:HGNC Symbol;Acc:1318]
Coordinates
chr19:6693016-6694645:-
Coord C1 exon
chr19:6694442-6694645
Coord A exon
chr19:6693423-6693498
Coord C2 exon
chr19:6693016-6693094
Length
76 bp
Sequences
Splice sites
3' ss Seq
TTCCTCTCTCTTCTCTGCAGGGT
3' ss Score
12.1
5' ss Seq
CTGGTGAGT
5' ss Score
10.1
Exon sequences
Seq C1 exon
GGACCCCAGTGGCCCAGATGACAGAGGATGCCGTCGACGCGGAACGGCTGAAGCACCTCATTGTGACCCCCTCGGGCTGCGGGGAACAGAACATGATCGGCATGACGCCCACGGTCATCGCTGTGCATTACCTGGATGAAACGGAGCAGTGGGAGAAGTTCGGCCTAGAGAAGCGGCAGGGGGCCTTGGAGCTCATCAAGAAGG
Seq A exon
GGTACACCCAGCAGCTGGCCTTCAGACAACCCAGCTCTGCCTTTGCGGCCTTCGTGAAACGGGCACCCAGCACCTG
Seq C2 exon
GCTGACCGCCTACGTGGTCAAGGTCTTCTCTCTGGCTGTCAACCTCATCGCCATCGACTCCCAAGTCCTCTGCGGGGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125730-'36-38,'36-36,37-38=AN
Average complexity
A_S
Mappability confidence:
89%=100=80%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.014 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF105694=Thiol-ester_cl=WD(100=44.9),PF076789=A2M_comp=PU(0.4=1.4)
A:
PF076789=A2M_comp=FE(10.7=100)
C2:
PF076789=A2M_comp=FE(22.6=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGGGAACAGAACATGATCGG
R:
CGATGAGGTTGACAGCCAGAG
Band lengths:
175-251
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)