HsaEX6093467 @ hg38
Exon Skipping
Gene
ENSG00000123143 | PKN1
Description
protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405]
Coordinates
chr19:14469752-14471859:+
Coord C1 exon
chr19:14469752-14469814
Coord A exon
chr19:14469912-14469988
Coord C2 exon
chr19:14471581-14471859
Length
77 bp
Sequences
Splice sites
3' ss Seq
ACCCCTCCAACCCCCAACAGGGA
3' ss Score
8.27
5' ss Seq
AGGGTGAGG
5' ss Score
7.13
Exon sequences
Seq C1 exon
CTTTTATTCCGCCTGCGTGGTGCTGGGCCTACAGTTTCTTCACGAACACAAGATCGTCTACAG
Seq A exon
GGACCTGAAGTTGGACAATTTGCTCCTGGACACCGAGGGCTACGTCAAGATCGCAGACTTTGGCCTCTGCAAGGAGG
Seq C2 exon
ACTCTGGGCTGGGAAGCCCTGTTGGCCCGGCGCCTGCCACCGCCCTTTGTGCCCACGCTGTCCGGCCGCACCGACGTCAGCAACTTCGACGAGGAGTTCACCGGGGAGGCCCCCACACTGAGCCCGCCCCGCGACGCGCGGCCCCTCACAGCCGCGGAGCAGGCAGCCTTCCTGGACTTCGACTTCGTGGCCGGGGGCTGCTAGCCCCCTCCCCTGCCCCTGCCCCTGCCCCTGCCCGAGAGCTCTTAGTTTTTAAAAAGGCCTTTGGGATTTGCCGGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123143_MULTIEX1-5/9=4-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.477
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(11.7=100)
A:
PF0006920=Pkinase=FE(10.0=100)
C2:
PF0043319=Pkinase_C=WD(100=69.1)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTTTATTCCGCCTGCGTGGT
R:
CCGGTGAACTCCTCGTCGAAG
Band lengths:
167-244
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains