HsaEX6093675 @ hg38
Exon Skipping
Gene
ENSG00000127528 | KLF2
Description
Kruppel like factor 2 [Source:HGNC Symbol;Acc:HGNC:6347]
Coordinates
chr19:16324817-16327874:+
Coord C1 exon
chr19:16324817-16324998
Coord A exon
chr19:16325216-16326032
Coord C2 exon
chr19:16326856-16327874
Length
817 bp
Sequences
Splice sites
3' ss Seq
CATTGCCCTGTCGCCCGCAGCGC
3' ss Score
10.78
5' ss Seq
CAGGTGGGC
5' ss Score
8.07
Exon sequences
Seq C1 exon
CCGCGGCCCACAGAGCCGTCCCCGCCCGCCCGCGCCCCGACCAGCCCGGCCTCGGGCAGCCACTCACCGGTGTCCCCGTCCGCGTCCTTTCTCCCCGGGTCCCGGCCATGGCGCTGAGTGAACCCATCCTGCCGTCCTTCTCCACTTTCGCCAGCCCGTGCCGCGAGCGCGGCCTGCAGGAG
Seq A exon
CGCTGGCCGCGCGCCGAACCCGAGTCCGGCGGCACCGACGACGACCTCAACAGCGTGCTGGACTTCATCCTGTCCATGGGGCTGGATGGCCTGGGCGCCGAGGCCGCCCCGGAGCCGCCGCCGCCGCCCCCGCCGCCTGCGTTCTATTACCCCGAACCCGGCGCGCCCCCGCCCTACAGCGCCCCCGCGGGTGGCCTGGTGTCTGAGCTGCTGCGACCCGAGCTGGATGCGCCGCTGGGGCCCGCACTGCACGGCCGCTTTCTGCTGGCGCCGCCCGGCCGCCTGGTCAAGGCCGAGCCCCCTGAAGCGGACGGCGGCGGCGGCTACGGCTGCGCCCCCGGGCTGACCCGTGGACCGCGCGGCCTCAAGCGCGAGGGCGCCCCGGGCCCGGCGGCTTCGTGCATGCGAGGTCCCGGGGGCCGCCCCCCGCCGCCGCCCGACACACCGCCGCTCAGCCCCGACGGCCCCGCGCGCCTGCCCGCGCCCGGTCCGCGCGCCTCCTTCCCGCCGCCTTTCGGTGGCCCTGGTTTCGGCGCGCCCGGGCCCGGCCTGCATTACGCGCCGCCTGCGCCCCCAGCCTTCGGTCTCTTCGACGACGCGGCCGCCGCCGCGGCAGCCCTGGGCCTGGCGCCCCCCGCCGCCCGCGGTCTCCTCACGCCGCCTGCGTCCCCGCTGGAGCTGCTGGAGGCCAAGCCAAAGCGCGGCCGCCGCTCTTGGCCCCGCAAACGCACCGCCACTCACACCTGCAGCTACGCGGGCTGCGGCAAGACCTACACCAAGAGTTCGCATCTGAAGGCGCATCTGCGCACGCACACAG
Seq C2 exon
GTGAGAAGCCCTACCACTGCAACTGGGACGGCTGCGGCTGGAAGTTTGCGCGCTCAGACGAGCTCACGCGCCACTACCGAAAGCACACGGGCCACCGGCCATTCCAGTGCCATCTGTGCGATCGTGCCTTCTCGCGCTCCGATCACCTGGCGCTGCACATGAAACGGCACATGTAGCCGGGACGCCCCCGCCCACCTGCGCGCGGCCGTGGCGGGTCCCACGCGCCGGGCGCGGCCCCCTCCCAAACTGTGACTGGTATTTATTGGACCCAGAGAACCGGGCCGGGCACAGCGTGGCTACAGAGGGTCTCCCTCGATGACGACGACGACGACGCCACCACCCCAGCCCCCGTCTGTGACTGAAGGCCCGGTGGGAAAAGACCACGATCCTCCTTGACGAGTTTTGTTTTTCAAAATGGTGCAATAATTTAAGTGGCATCTTCTCTCCCACCGGGTCTACACTAGAGGATCGAGGCTTGTGATGCCTTGTGAGAAATAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000127528-'0-2,'0-0,3-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.250 A=0.817 C2=0.181
Domain overlap (PFAM):
C1:
NO
A:
PF134651=zf-H2C2_2=PU(35.7=3.7)
C2:
PF134651=zf-H2C2_2=PD(60.7=28.8),PF134651=zf-H2C2_2=WD(100=44.1)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCCTTCTCCACTTTCGCCAG
R:
CTCTGTAGCCACGCTGTGC
Band lengths:
353-1170
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains