HsaEX6095707 @ hg19

Exon Skipping

Gene

ENSG00000104936 | DMPK

Description

dystrophia myotonica-protein kinase [Source:HGNC Symbol;Acc:2933]

Coordinates

chr19:46275029-46278292:-

Coord C1 exon

chr19:46278207-46278292

Coord A exon

chr19:46275899-46276010

Coord C2 exon

chr19:46275029-46275186

Length

112 bp

Sequences

Splice sites

3' ss Seq

CTCCCTCCTCCTCTCCCCAGGGA

3' ss Score

12.87

5' ss Seq

ACAGTAAGT

5' ss Score

9.49

Exon sequences

Seq C1 exon

GAGACACTGTCGGACATTCGGGAAGGTGCGCCGCTAGGGGTCCACCTGCCTTTTGTGGGCTACTCCTACTCCTGCATGGCCCTCAG

Seq A exon

GGACAGTGAGGTCCCAGGCCCCACACCCATGGAACTGGAGGCCGAGCAGCTGCTTGAGCCACACGTGCAAGCGCCCAGCCTGGAGCCCTCGGTGTCCCCACAGGATGAAACA

Seq C2 exon

GCTGAAGTGGCAGTTCCAGCGGCTGTCCCTGCGGCAGAGGCTGAGGCCGAGGTGACGCTGCGGGAGCTCCAGGAAGCCCTGGAGGAGGAGGTGCTCACCCGGCAGAGCCTGAGCCGGGAGATGGAGGCCATCCGCACGGACAACCAGAACTTCGCCAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000104936-'12-14,'12-13,13-14=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.152 A=0.947 C2=0.955

Domain overlap (PFAM):

C1:

NO

A:

PF104814=CENP-F_N=PU(26.9=73.7),PF041569=IncA=PU(18.5=52.6),PF0126119=AP_endonuc_2=PU(0.6=2.6)

C2:

PF104814=CENP-F_N=FE(50.5=100),PF041569=IncA=FE(49.5=100),PF136001=DUF4140=FE(53.6=100),PF0126119=AP_endonuc_2=FE(44.1=100),PF093045=Cortex-I_coil=PU(59.5=88.7),PF102674=Tmemb_cc2=FE(50.5=100),PF0157614=Myosin_tail_1=FE(54.7=100),PF032458=Phage_lysis=PU(40.0=79.2),PF154781=LKAAEAR=FE(56.5=100),PF060097=Laminin_II=PU(57.8=90.6),PF088265=DMPK_coil=PU(50.8=58.5),PF139491=ALIX_LYPXL_bnd=PU(44.4=83.0)

Main Inclusion Isoform:

ENSP00000345997