MmuEX0014891 @ mm10
Exon Skipping
Gene
ENSMUSG00000030409 | Dmpk
Description
dystrophia myotonica-protein kinase [Source:MGI Symbol;Acc:MGI:94906]
Coordinates
chr7:19088911-19091844:+
Coord C1 exon
chr7:19088911-19088996
Coord A exon
chr7:19090929-19091040
Coord C2 exon
chr7:19091681-19091844
Length
112 bp
Sequences
Splice sites
3' ss Seq
TAGCCTCTTCCTCTTCTCAGAGA
3' ss Score
7.94
5' ss Seq
GTGGTGAGT
5' ss Score
8.95
Exon sequences
Seq C1 exon
GAGACGCTGTCAGACATGCAGGAAGACATGCCCCTTGGGGTGCGCCTGCCCTTCGTGGGCTACTCCTACTGCTGCATGGCCTTCAG
Seq A exon
AGACAATCAGGTCCCGGACCCCACCCCTATGGAACTAGAGGCCCTGCAGTTGCCTGTGTCAGACTTGCAAGGGCTTGACTTGCAGCCCCCAGTGTCCCCACCGGATCAAGTG
Seq C2 exon
GCTGAAGAGGCTGACCTAGTGGCTGTCCCTGCCCCTGTGGCTGAGGCAGAGACCACGGTAACGCTGCAGCAGCTCCAGGAAGCCCTGGAAGAAGAGGTTCTCACCCGGCAGAGCCTGAGCCGCGAGCTGGAGGCCATCCGGACCGCCAACCAGAACTTCTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030409_CASSETTE5
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.233 A=0.684 C2=0.745
Domain overlap (PFAM):
C1:
NO
A:
PF041569=IncA=PU(26.2=84.2)
C2:
PF041569=IncA=FE(44.3=100),PF088265=DMPK_coil=PU(50.8=56.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGACGCTGTCAGACATGCAG
R:
GAGAAGTTCTGGTTGGCGGTC
Band lengths:
247-359
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types