HsaEX6101419 @ hg38
Exon Skipping
Gene
ENSG00000131187 | F12
Description
coagulation factor XII [Source:HGNC Symbol;Acc:HGNC:3530]
Coordinates
chr5:177405323-177406061:-
Coord C1 exon
chr5:177405962-177406061
Coord A exon
chr5:177405735-177405805
Coord C2 exon
chr5:177405323-177405433
Length
71 bp
Sequences
Splice sites
3' ss Seq
AGCCTTGTCTCTTTCTACAGGTG
3' ss Score
11.15
5' ss Seq
AAGGTGCTA
5' ss Score
2.48
Exon sequences
Seq C1 exon
TTCTCACTGTCACCGGGGAGCCCTGCCACTTCCCCTTCCAGTACCACCGGCAGCTGTACCACAAATGTACCCACAAGGGCCGGCCAGGCCCTCAGCCCTG
Seq A exon
GTGTGCTACCACCCCCAACTTTGATCAGGACCAGCGATGGGGATACTGTTTGGAGCCCAAGAAAGTGAAAG
Seq C2 exon
ACCACTGCAGCAAACACAGCCCCTGCCAGAAAGGAGGGACCTGTGTGAACATGCCAAGCGGCCCCCACTGTCTCTGTCCACAACACCTCACTGGAAACCACTGCCAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131187-'4-6,'4-4,5-6
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.029 A=0.100 C2=0.283
Domain overlap (PFAM):
C1:
PF0004014=fn2=PU(59.5=73.5)
A:
PF0004014=fn2=PD(38.1=64.0)
C2:
PF0000822=EGF=WD(100=84.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCACTTCCCCTTCCAGTACCA
R:
CCAGTGAGGTGTTGTGGACAG
Band lengths:
169-240
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains