MmuEX6058592 @ mm10
Exon Skipping
Gene
ENSMUSG00000021492 | F12
Description
coagulation factor XII (Hageman factor) [Source:MGI Symbol;Acc:MGI:1891012]
Coordinates
chr13:55418352-55426360:-
Coord C1 exon
chr13:55426303-55426360
Coord A exon
chr13:55422406-55422476
Coord C2 exon
chr13:55418352-55418500
Length
71 bp
Sequences
Splice sites
3' ss Seq
AAACCTCATCTATCCCCCAGGTG
3' ss Score
9.12
5' ss Seq
AAGGTATGT
5' ss Score
9.79
Exon sequences
Seq C1 exon
GCTCCACCATGGAAAGACTCCAAGAAATTTAAGGACGCACCTGATGGGCCCACAGTGG
Seq A exon
GTGTGCTACCACCCCCAACTTTGATGAAGATCAGCAATGGGGATACTGCTTGGAGCCCAAGAAAGTGAAAG
Seq C2 exon
GGGCTGAAGAATACTCCACCTTCCTGCAGGAGGCACAGGTTCCCTTTATCGCCCTGGATCGCTGCTCCAACTCTAACGTGCACGGAGACGCCATTCTCCCTGGGATGCTTTGCGCTGGCTTCTTGGAGGGAGGCACCGATGCCTGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000021492_MULTIEX1-2/10=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.275 A=0.000 C2=0.010
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(5.7=30.0)
A:
PF0004014=fn2=PD(38.1=64.0)
C2:
PF0008921=Trypsin=FE(20.7=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCAAGAAATTTAAGGACGCACC
R:
CTCCAAGAAGCCAGCGCAAAG
Band lengths:
168-239
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types