HsaEX6101425 @ hg38
Exon Skipping
Gene
ENSG00000131187 | F12
Description
coagulation factor XII [Source:HGNC Symbol;Acc:HGNC:3530]
Coordinates
chr5:177403254-177404090:-
Coord C1 exon
chr5:177403859-177404090
Coord A exon
chr5:177403481-177403617
Coord C2 exon
chr5:177403254-177403397
Length
137 bp
Sequences
Splice sites
3' ss Seq
CTCCCCTACCCCCCCCGCAGGCC
3' ss Score
11.59
5' ss Seq
TGGGTGCGT
5' ss Score
5.46
Exon sequences
Seq C1 exon
CCTTGCCGGCGAAGCGGGAGCAGCCGCCTTCCCTGACCAGGAACGGCCCACTGAGCTGCGGGCAGCGGCTCCGCAAGAGTCTGTCTTCGATGACCCGCGTCGTTGGCGGGCTGGTGGCGCTACGCGGGGCGCACCCCTACATCGCCGCGCTGTACTGGGGCCACAGTTTCTGCGCCGGCAGCCTCATCGCCCCCTGCTGGGTGCTGACGGCCGCTCACTGCCTGCAGGACCG
Seq A exon
GCCCGCACCCGAGGATCTGACGGTGGTGCTCGGCCAGGAACGCCGTAACCACAGCTGTGAGCCGTGCCAGACGTTGGCCGTGCGCTCCTACCGCTTGCACGAGGCCTTCTCGCCCGTCAGCTACCAGCACGACCTGG
Seq C2 exon
CTCTGTTGCGCCTTCAGGAGGATGCGGACGGCAGCTGCGCGCTCCTGTCGCCTTACGTTCAGCCGGTGTGCCTGCCAAGCGGCGCCGCGCGACCCTCCGAGACCACGCTCTGCCAGGTGGCCGGCTGGGGCCACCAGTTCGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131187-'13-19,'13-17,15-19=AN
Average complexity
A_S
Mappability confidence:
88%=75=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.218 A=0.064 C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(18.6=56.4)
A:
PF0008921=Trypsin=FE(19.4=100)
C2:
PF0008921=Trypsin=FE(20.3=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAACGGCCCACTGAGCTG
R:
CTGAACGTAAGGCGACAGGAG
Band lengths:
254-391
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains