HsaEX7104717 @ hg38
Exon Skipping
Gene
ENSG00000126522 | ASL
Description
argininosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:746]
Coordinates
chr7:66087729-66089175:+
Coord C1 exon
chr7:66087729-66087791
Coord A exon
chr7:66088807-66088921
Coord C2 exon
chr7:66089091-66089175
Length
115 bp
Sequences
Splice sites
3' ss Seq
CTGGGAACCTTTTCTCCCAGCCG
3' ss Score
3.11
5' ss Seq
CAGGTAAGC
5' ss Score
9.88
Exon sequences
Seq C1 exon
AACTCAACTTTGGGGCCATCACTCTCAACAGCATGGATGCCACTAGTGAGCGGGACTTTGTGG
Seq A exon
CCGAGTTCCTGTTCTGGGCTTCGCTGTGCATGACCCATCTCAGCAGGATGGCCGAGGACCTCATCCTCTACTGCACCAAGGAATTCAGCTTCGTGCAGCTCTCAGATGCCTACAG
Seq C2 exon
CACGGGAAGCAGCCTGATGCCCCAGAAGAAAAACCCCGACAGTTTGGAGCTGATCCGGAGCAAGGCTGGGCGTGTGTTTGGGCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126522-'17-42,'17-31,28-42=AN
Average complexity
A_C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.069
Domain overlap (PFAM):
C1:
PF0020615=Lyase_1=FE(19.6=100)
A:
PF0020615=Lyase_1=FE(12.9=100)
C2:
PF0020615=Lyase_1=PD(11.2=90.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGCAGACTTGGGGGAAAACA
R:
GAAACACACAGCAGCCTCCTC
Band lengths:
250-365
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains