HsaINT0000082 @ hg38
Intron Retention
Gene
ENSG00000166535 | A2ML1
Description
alpha-2-macroglobulin like 1 [Source:HGNC Symbol;Acc:HGNC:23336]
Coordinates
chr12:8868230-8868627:+
Coord C1 exon
chr12:8868230-8868357
Coord A exon
chr12:8868358-8868536
Coord C2 exon
chr12:8868537-8868627
Length
179 bp
Sequences
Splice sites
5' ss Seq
CAGGTGATT
5' ss Score
5.95
3' ss Seq
TTTCTTCTTCCTGCTCTCAGTTA
3' ss Score
9.66
Exon sequences
Seq C1 exon
ACGGTGTTGAGATACAATATTCTCCCTCCCACAAATATGAAGACCTTTAGTCTTAGTGTGGAAATAGGAAAAGCTAGATGTGAGCAACCGACTTCACCTCGATCCTTGACTCTCACTATTCACACCAG
Seq A exon
GTGATTAAAGCTGGGGTGCTGGTGGCCGGCAGAGCACCTGGTCATAGGAGCTGAGCTGGGACACTTGTGTGTGTGTGTGTCTGTGTATGTGTGTGTGTACGTGTGTGTGTGTGTGTGTTGGGGATGCAGAGTGCACTGAAGTAATAGGCTCACATGTGTTTTCTTCTTCCTGCTCTCAG
Seq C2 exon
TTATGTGGGGAGCCGTAGCTCTTCCAATATGGCTATTGTGGAAGTGAAGATGCTATCTGGGTTCAGTCCCATGGAGGGCACCAATCAGTTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166535:ENST00000299698:31
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF076779=A2M_recep=PU(25.0=71.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGGTGTTGAGATACAATATTCTCCC
R:
AACTGATTGGTGCCCTCCATG
Band lengths:
218-397
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development