HsaINT0000641 @ hg19
Intron Retention
Gene
ENSG00000167972 | ABCA3
Description
ATP-binding cassette, sub-family A (ABC1), member 3 [Source:HGNC Symbol;Acc:33]
Coordinates
chr16:2335443-2336968:-
Coord C1 exon
chr16:2336695-2336968
Coord A exon
chr16:2335648-2336694
Coord C2 exon
chr16:2335443-2335647
Length
1047 bp
Sequences
Splice sites
5' ss Seq
CGAGTATGT
5' ss Score
6.61
3' ss Seq
ACCTTCTCTGTCCCCCGCAGGGG
3' ss Score
12.9
Exon sequences
Seq C1 exon
GTGACCTGGAGGAGTTCTTGATCTTCAGGGCTTCTGTGGAGGGGGGCGGCTTTAATGAGCGGTGCCTTGTGGCAGCGTCCTTCAGAGATGTGGGAGAGCGCACGGTCGTCAACGCCTTGTTCAACAACCAGGCGTACCACTCTCCAGCCACTGCCCTGGCCGTCGTGGACAACCTTCTGTTCAAGCTGCTGTGCGGGCCTCACGCCTCCATTGTGGTCTCCAACTTCCCCCAGCCCCGGAGCGCCCTGCAGGCTGCCAAGGACCAGTTTAACGA
Seq A exon
GTATGTGCACTGCCCGTCCCTGTCTGCCCTGGCCAGAGCCCCCAGGACTGACTGCCCTGGGCACTGCCACGGGCCCATAGATAGAGCATTGTGTCTGCCCTCCCAAAGCCCCTGGGTCTGGTGGGAAACCCCTGCCACATCCTCCTCCACCATCCACAGCCCCAACTCCCTGTGACAGCAGATCAGCTGTGGGCCATCCCATGCACTGCGGTCCTCACGGGGACCCATGAAGGCTCGGCAGGCAGCCCTGCCTTCTCCTCCTAAATCTACCTGGCTCCTGTCAGCCACTGTCCTCGCTCCACACTGCTCTCTCCAGCAGTGTGACCTGCTGGGCACATGAGCTGAGGTGATGGAGGGTGAGCAGAGCAGGACTTGGCAAGAACTGCCGTCCCTGTTCCTCAGATGGCCGCACGTCGGGAGCCTGCCATGCCATTGTGTGGGCAGGGCTACCCCCTATGCCGGCCACAGAGCCCCCAGAGCTCCTGGAACCACCCAGAGGAGGCCAAAAATTCTGTTAATTTCAGAATAGCCACTCCTCCTCAGGGCAGTGTCGTCTCCACCCACATTCCAGGCTAGGCCTAGGCCTGGCGATGGCTGCGTCCCAGCTTCTGGCTCCATCCCTGCCCCAAGAGCAGAAAAGCAACAGCCCTCGATCTGCTCTCCTTGCCATCAACTCAGGATCCTAGAATGACACACAGAGGCCAGGAGAGGCTTTCCCTTTGCCACACTCCAGGAGGAGGTGGGGCTCGGGACCTCCACACCTGGGCAAGGTCGCCGGCAGCCGTGGGGCTGAGGGCTGGGAGCGGGGTGATGAGGGAGAGTGACGCTGCCATTGTCACATGGTCAGCATAGGAATTCCAGAGGAACCGTTCTCCGGTGGGGGCAGATGTTCCCGGTATGGAACCATGGTGCTTGTGCTCTCCCATAAGCCCCTTTAGTGGTTGGGCTGCTGCCCTGCATGCCTTGGGCGGTCATAACCGAGAACCCGACCTCTCCTGCCACCCAGACGTGCTGTGCTCCGTCCCTGACCTTCTCTGTCCCCCGCAG
Seq C2 exon
GGGCCGGAAGGGATTCGACATTGCCCTCAACCTGCTCTTCGCCATGGCATTCTTGGCCAGCACGTTCTCCATCCTGGCGGTCAGCGAGAGGGCCGTGCAGGCCAAGCATGTGCAGTTTGTGAGTGGAGTCCACGTGGCCAGTTTCTGGCTCTCTGCTCTGCTGTGGGACCTCATCTCCTTCCTCATCCCCAGTCTGCTGCTGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167972-ABCA3:NM_001089:22
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF126982=ABC2_membrane_3=FE(22.6=100)
A:
NA
C2:
PF126982=ABC2_membrane_3=FE(16.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCGTCAACGCCTTGTTCAACA
R:
GGAAGGAGATGAGGTCCCACA
Band lengths:
351-1398
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)